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Documentos Principais

PHR1350

Supelco

Cytosine

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Cytosine, 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

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500 MG
R$ 1.846,00

R$ 1.846,00


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500 MG
R$ 1.846,00

About This Item

Fórmula empírica (Notação de Hill):
C4H5N3O
Número CAS:
Peso molecular:
111.10
Beilstein:
2637
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

R$ 1.846,00


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grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to USP 1162148

família API

cytosine

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

>300 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

NC1=NC(=O)NC=C1

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

chave InChI

OPTASPLRGRRNAP-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Cytosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary zone electrophoresis[1] and chromatography[2] techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA1102 in the slot below. This is an example certificate only and may not be the lot that you receive.

produto relacionado

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Characterization of alkaloids in Sophora flavescens Ait. by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry
Liu G, et al.
Journal of Pharmaceutical and Biomedical Analysis, 54(5), 1065-1072 (2011)
Development and validation of a procedure for the determination of minoxidil in hair-regrowth formulations using two variants of capillary zone electrophoresis
Patterson SC, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(6-7), 547-554 (2005)
Gitali Devi et al.
Nucleic acids research, 42(6), 4008-4018 (2014-01-16)
Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological
C P Walsh et al.
Current topics in microbiology and immunology, 301, 283-315 (2006-03-31)
Cytosine methylation is a common form of post-replicative DNA modification seen in both bacteria and eukaryotes. Modified cytosines have long been known to act as hotspots for mutations due to the high rate of spontaneous deamination of this base to
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Epigenetic genome marking and chromatin regulation are central to establishing tissue-specific gene expression programs, and hence to several biological processes. Until recently, the only known epigenetic mark on DNA in mammals was 5-methylcytosine, established and propagated by DNA methyltransferases and

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