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1602502

USP

Retinyl palmitate

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

Vitamin A palmitate, all−trans−Retinol palmitate

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About This Item

Fórmula empírica (Notação de Hill):
C36H60O2
Número CAS:
Peso molecular:
524.86
Beilstein:
1917366
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

retinyl compounds

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

chave InChI

VYGQUTWHTHXGQB-FFHKNEKCSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação


  • Retinyl palmitate in nanoemulgels for skin diseases: Research explores the application of retinyl palmitate in innovative nanoemulgels, demonstrating its efficacy in treating skin conditions through enhanced delivery mechanisms. This aligns with its use in skin rejuvenation and anti-aging treatments, providing a novel approach for topical therapy (Sghier et al., 2024).

  • Stability and efficacy in UVB-induced skin photoaging: A study assessed retinyl palmitate′s efficacy against UVB-induced photoaging, showing significant protective effects on the skin. This underscores its potential as a high-purity biochemical assay component for studying retinoid signaling and its impact on skin health (Shu et al., 2023).

  • Enhanced anti-photoaging therapy: Comparative research among various retinoids, including retinyl palmitate, highlights its superior anti-inflammatory and antioxidative activities, positioning it as a preferred choice for anti-photoaging treatments. The study emphasizes its application in biochemical assays and as a vitamin A source in tissue engineering (Shu et al., 2023).

Ações bioquímicas/fisiológicas

Review: Vitamin A metabolism.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Aquatic Chronic 3 - Repr. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

381.2 °F

Ponto de fulgor (°C)

194.00 °C


Certificados de análise (COA)

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Phytonadione

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Vitamin A
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(2), 4632-4632 (2019)
Shaikh Meshbahuddin Ahmad et al.
Contemporary clinical trials, 39(2), 269-279 (2014-10-02)
In recent years, neonatal vitamin A supplementation is considered as an essential infant-survival intervention but the evidence is not conclusive. This randomized controlled clinical trial was conducted to evaluate the effect of vitamin A on immune competence in early infancy.
Hans L Mooij et al.
Journal of lipid research, 56(3), 665-673 (2015-01-09)
Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous
Xiaofeng Liao et al.
PloS one, 10(3), e0118176-e0118176 (2015-03-17)
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood. Here we demonstrate that tRA have paradoxical effects on

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