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1508901

USP

Pentoxifylline

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

3,7-Dimethyl-1-(5-oxohexyl)xanthine, Trental

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About This Item

Fórmula empírica (Notação de Hill):
C13H18N4O3
Número CAS:
6493-05-6
Peso molecular:
278.31
Número MDL:
MFCD00063379
Código UNSPSC:
41116107
ID de substância PubChem:
329750705
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

pentoxifylline

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

CN1C=NC2C1C(=O)N(CCCCC(C)=O)C(=O)N2C

InChI

1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8,10-11H,4-7H2,1-3H3

chave InChI

MQGNNJQTNFHNHK-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Pentoxifylline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Pentoxifylline Compounded Oral Suspension
  • Pentoxifylline Extended-Release Tablets

Ações bioquímicas/fisiológicas

Phosphodiesterase inhibitor; inhibits synthesis of tumor necrosis factor α (TNF-α).

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302,H362

Classificações de perigo

Acute Tox. 4 Oral - Lact.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Andrew B Jull et al.
The Cochrane database of systematic reviews, 12, CD001733-CD001733 (2012-12-14)
Healing of venous leg ulcers is improved by the use of compression bandaging but some venous ulcers remain unhealed, and some people are unsuitable for compression therapy. Pentoxifylline, a drug which helps blood flow, has been used to treat venous
Dan Shan et al.
The Cochrane database of systematic reviews, 2(2), CD006800-CD006800 (2012-02-18)
Diabetic kidney disease (DKD) is associated with increased morbidity and mortality, mostly relating to cardiovascular complications. The relevance of inflammation in the pathogenesis of DKD has been investigated in recent years, and it has been shown that inflammatory markers are
R Parker et al.
Alimentary pharmacology & therapeutics, 37(9), 845-854 (2013-03-16)
Acute alcoholic hepatitis (AH) is a severe manifestation of alcoholic liver disease with a grave prognosis. Pentoxifylline, an oral antitumour necrosis factor agent, has been reported to reduce mortality and incidence of hepatorenal syndrome (HRS) in severe alcoholic hepatitis (SAH).
Donghao Lu et al.
The Cochrane database of systematic reviews, 1, CD007677-CD007677 (2012-01-20)
Endometriosis is a chronic, recurring condition that occurs during the reproductive years. It is characterized by endometrial tissue developing outside the uterine cavity. This endometrial tissue development is dependent on oestrogen produced primarily by the ovaries and, therefore, traditional management
Wenjun Li et al.
Lipids in health and disease, 10, 49-49 (2011-04-12)
As an anti-TNF agent that targets inflammatory process directly, Pentoxifylline has been investigated for treatment of NASH in individual studies and pilot trials for years. We summarized the available information and generating hypotheses for future research. Google, Cochrane, MEDLINE, and
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