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V0131

Sigma-Aldrich

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat

≥97% (HPLC)

Sinônimo(s):

VIP 1-12

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About This Item

Fórmula empírica (Notação de Hill):
C61H88N18O22
Número CAS:
120928-03-2
Peso molecular:
1425.46
Número MDL:
MFCD00133921
Código UNSPSC:
12352200
ID de substância PubChem:
24900690
NACRES:
NA.26

Nome do produto

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat, ≥97% (HPLC)

Nível de qualidade

200

Ensaio

≥97% (HPLC)

Formulário

solid

nº de adesão UniProt

P01282

aplicação(ões)

cell analysis

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC(C)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C61H88N18O22/c1-27(2)46(77-49(89)28(3)69-51(91)40(22-44(85)86)73-56(96)42(25-80)76-50(90)35(62)20-33-24-66-26-68-33)57(97)74-38(18-31-10-7-6-8-11-31)55(95)79-48(30(5)82)59(99)75-41(23-45(87)88)53(93)72-39(21-43(63)84)52(92)71-37(19-32-13-15-34(83)16-14-32)54(94)78-47(29(4)81)58(98)70-36(60(100)101)12-9-17-67-61(64)65/h6-8,10-11,13-16,24,26-30,35-42,46-48,80-83H,9,12,17-23,25,62H2,1-5H3,(H2,63,84)(H,66,68)(H,69,91)(H,70,98)(H,71,92)(H,72,93)(H,73,96)(H,74,97)(H,75,99)(H,76,90)(H,77,89)(H,78,94)(H,79,95)(H,85,86)(H,87,88)(H,100,101)(H4,64,65,67)

chave InChI

OZQVVUDUPMJWPH-UHFFFAOYSA-N

Informações sobre genes

human ... VIP(7432)

Amino Acid Sequence

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg

Ações bioquímicas/fisiológicas

Ligand for CD4 receptor.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
118K8724
048K1292
067K1846
076K13691
095K11621

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K J Sung et al.
Neuropeptides, 33(6), 435-446 (2000-02-05)
It is well known that psoriasis, an immunogenetic cutaneous disorder whose major pathogenic findings are epidermal hyperplasia and T-cell infiltration, is aggravated by psychological stresses. Although the exact mechanism is not yet clarified, antidromic secretion of neuropeptides by cutaneous nerve
M Ichinose et al.
Regulatory peptides, 54(2-3), 457-466 (1994-12-15)
The effect of VIP on phagocytosis in peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that VIP suppressed phagocytosis in a dose-dependent manner. VIP(1-12) did not suppress phagocytosis. VIP(10-28) was more suppressive than VIP(1-28). A
F Séjourné et al.
The American journal of physiology, 273(1 Pt 2), R287-R292 (1997-07-01)
The purpose of this study was to begin to determine the mechanisms underlying vasodilation elicited by vasoactive intestinal peptide (VIP) in sterically stabilized liposomes (SSL) in the in situ peripheral microcirculation. Using intravital microscopy, we found that suffusion of VIP
S Chakder et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 392-399 (1993-07-01)
Because no significant information exists regarding the structure-activity of vasoactive intestinal polypeptide (VIP) to gut smooth muscle, we performed functional studies in vitro on opossum internal anal sphincter (IAS) smooth muscle strips and supplemented them with binding studies to assess
P Sacerdote et al.
Journal of neuroscience research, 18(1), 102-107 (1987-01-01)
A five-amino-acid (TDNYT) sequence of vasoactive intestinal polypeptide (VIP) shares homology with the proposed attachment sequences of the human immunodeficiency virus (HIV). Synthetic peptides with these sequences have previously been shown to block viral envelope (gp120) binding and HIV infectivity

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