T3526

Anti-TUBA1B (alpha-tubulin ubiquitous) Antibody

rabbit polyclonal

• Sinônimo(s): Anti-K-ALPHA-1
• Número MDL: MFCD00145921
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• Nome do produto: Anti-Tubulin antibody produced in rabbit, whole antiserum
• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: whole antiserum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• contém: 15 mM sodium azide
• reatividade de espécies: chicken, mouse
• técnica(s): indirect immunofluorescence: 1:80 using cultured fibroblasts; western blot: 1:200 using chicken gizzard extract or mouse brain extract
• nº de adesão UniProt: P68363
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: mouse ... Tuba1b(22143) , Tubb2a(22151) , Tubb2b(73710) , Tubb2c(227613)

Descrição

Descrição geral

Microtubules are composed of tubulin and several additional proteins designated microtubule associated proteins (MAPs). Tubulin is a heterodimer which consists of an α-chain and a β-chain, both of which have a molecular weight of approximately 55,000. Microtubules form an elaborate cytoplasmic network during interphase and are reorganized into the mitotic spindle during cell division.

Tubulin is an extremely conserved and negatively charged protein. It is expressed in all eukaryotic cells, but mainly in brains.

Especificidade

The product stains tubulin in cultured chicken fibroblasts or 3T3 mouse fibroblasts. Additional bands may be stained in immunoblotting.

Imunogênio

microtubule proteins from brains of 13 day old chicken embryos

Aplicação

Anti-Tubulin antibody produced in rabbit has been used in immunoblotting and indirect immunofluorescence.

Ações bioquímicas/fisiológicas

αβ-tubulin heterodimers helps in formation of microtubules. Tubulin dimers exhibits GTPase activity, assembly and disassembly properties. It facilitates the construction of the flagellar apparatus.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)