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T2402

Sigma-Aldrich

Anti-Mouse IgG (whole molecule)−TRITC antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sinônimo(s):

Rabbit Anti-Mouse IgG (whole molecule)−Tetramethylrhodamine isothiocyanate

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2 ML
R$ 2.825,00

R$ 2.825,00


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2 ML
R$ 2.825,00

About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

R$ 2.825,00


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fonte biológica

rabbit

conjugado

TRITC conjugate

forma do anticorpo

IgG fraction of antiserum

tipo de produto de anticorpo

secondary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

condição de armazenamento

protect from light

técnica(s)

direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Categorias relacionadas

Descrição geral

Immunoglobulins (Igs) belongs immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L), held together by disulphide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. IgG is abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

Especificidade

Anti-Mouse IgG (whole molecule)-TRITC antibody is specific for mouse IgG.

Imunogênio

Normal mouse serum

Aplicação

Anti-Mouse IgG (whole molecule)-TRITC antibody is suitable for use in direct immunofluorescence (1:64), immunohistochemistry (1:200 dilution in formalin-fixed, paraffin-embedded sections), Ouchterlony double diffusion and electrophoresis techniques.

Ações bioquímicas/fisiológicas

Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallizable (fc), comprises the H chain constant region.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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