T1694
(E)-4-Amino-2-butenoic acid
Sinônimo(s):
trans-4-Aminocrotonic acid, TACA
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About This Item
Fórmula empírica (Notação de Hill):
C4H7NO2
Número CAS:
Peso molecular:
101.10
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NA.77
Produtos recomendados
forma
powder
cor
white
solubilidade
H2O: 10 mg/mL, clear
cadeia de caracteres SMILES
NC\C=C\C(O)=O
InChI
1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1+
chave InChI
FMKJUUQOYOHLTF-OWOJBTEDSA-N
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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M Kurjak et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 23(5), e181-e190 (2011-03-19)
γ-Aminobutyric acid (GABA) acts on specific neural receptors [A, B and C(Aρ)] to modulate gastrointestinal function. The precise role of GABA receptor activation in the regulation of presynaptic nitric oxide (NO) synthesis in nerve terminals is unknown. Rat ileal nerve
Ralph J Jensen
PloS one, 8(10), e79126-e79126 (2013-11-10)
Retinitis pigmentosa (RP) is a progressive retinal degenerative disease that causes deterioration of rod and cone photoreceptors. A well-studied animal model of RP is the transgenic P23H rat, which carries a mutation in the rhodopsin gene. Previously, I reported that
Kinga K Borowicz et al.
Pharmacological reports : PR, 57(1), 121-123 (2005-04-26)
In the present study, we evaluated TACA (a potent agonist of GABA(A) and GABA(C) receptors) in the electroconvulsive threshold test in mice. Surprisingly, TACA (at 15 and 25 mg/kg) significantly decreased the threshold. The highest ineffective dose of TACA was
D Zhang et al.
Trends in pharmacological sciences, 22(3), 121-132 (2001-03-10)
In less than a decade our knowledge of the GABA(C) receptor, a new type of Cl(-)-permeable ionotropic GABA receptor, has greatly increased based on studies of both native and recombinant receptors. Careful comparison of properties of native and recombinant receptors
M Chebib et al.
British journal of pharmacology, 122(8), 1551-1560 (1998-01-10)
1. gamma-Aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) have been shown to activate GABAC receptors. In this study, a range of C2, C3, C4 and N-substituted GABA and TACA analogues were examined for activity at GABAC receptors. 2. The effects
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