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T133

Sigma-Aldrich

Inactin® hydrate

≥98% (HPLC)

Sinônimo(s):

Thiobutabarbital sodium salt hydrate

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About This Item

Fórmula empírica (Notação de Hill):
C10H15N2NaO2S · xH2O
Número CAS:
947-08-0
Peso molecular:
250.29 (anhydrous basis)
Número CE:
213-425-3
Número MDL:
MFCD00214068
Código UNSPSC:
12352200
ID de substância PubChem:
24899957
NACRES:
NA.77

Nível de qualidade

100

Ensaio

≥98% (HPLC)

forma

powder

controle de medicamentos

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

cor

light yellow

solubilidade

H2O: soluble (storage of solutions for more than 8 hours at 4°C is not recommended.)

cadeia de caracteres SMILES

[Na+].CCC(C)C1(CC)C([O-])=NC(=S)NC1=O

InChI

1S/C10H16N2O2S.Na/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14;/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15);/q;+1/p-1

chave InChI

SLZHLQUFNFXTHB-UHFFFAOYSA-M

Aplicação

Inactin® hydrate has been used to anesthetize rats to study stress-induced hypersensitivity and mice to study Cisplatin-induced neuropathy. It has also been used to anesthetize rats to measure the glomerular filtration rate (GFR).

Ações bioquímicas/fisiológicas

Inactin® is a long-lasting rodent anesthetic with minimal effects on cardiovascular tone and renal output. It exhibits sedative and hypnotic properties.

Informações legais

Inactin is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Maki Niihori et al.
American journal of respiratory cell and molecular biology, 62(2), 231-242 (2019-08-29)
NFU1 is a mitochondrial protein that is involved in the biosynthesis of iron-sulfur clusters, and its genetic modification is associated with disorders of mitochondrial energy metabolism. Patients with autosomal-recessive inheritance of the NFU1 mutation G208C have reduced activity of the
Min-Suk Yoon et al.
BMC neuroscience, 10, 77-77 (2009-07-16)
Cisplatin mediates its antineoplastic activity by formation of distinct DNA intrastrand cross links. The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA lesions in dorsal root ganglion (DRG) cells leading to sensory polyneuropathy
Flecknell
Laboratory Animal Anesthesia. An introduction for Research Workers and Technicians, 36-36 (1987)
A C Ailiani et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(10), 1477-1486 (2014-09-27)
Anesthetics are commonly applied in animal studies of gastrointestinal (GI) function. Different anesthetics alter smooth-muscle motility in different ways. The aim of this study is to quantify and compare non-invasively with magnetic resonance imaging (MRI) the motility patterns of the
Olga Rafikova et al.
Biology of sex differences, 11(1), 11-11 (2020-03-20)
The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more severe disease with poor survival prognosis in
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