Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

SRP6153

Sigma-Aldrich

Activin A human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

Sinônimo(s):

FRP, FSH-releasing protein, Inhibin beta A

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Número CAS:
104625-48-1
Código UNSPSC:
12352202
NACRES:
NA.32

fonte biológica

human

recombinante

expressed in human cells

Ensaio

≥95% (SDS-PAGE)

forma

lyophilized

peso molecular

25 kDa (homodimer, non-glycosylated)

embalagem

pkg of 10 μg

nº de adesão NCBI

P08476

Condições de expedição

dry ice

temperatura de armazenamento

−70°C

InChI

1S/C27H34O3/c1-27-16-15-22-21-11-9-20(28)17-19(21)8-10-23(22)24(27)12-13-25(27)30-26(29)14-7-18-5-3-2-4-6-18/h2-6,17,21-25H,7-16H2,1H3

chave InChI

UBWXUGDQUBIEIZ-UHFFFAOYSA-N

Informações sobre genes

human ... INHBA(3624)

Descrição geral

Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-? super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision′s Activin A is produced in a serum-free, chemically de?ned media.

forma física

Lyophilized from a PBS solution.

Nota de preparo

Centrifuge the vial prior to opening.

Reconstituição

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Yan Li et al.
The Journal of clinical endocrinology and metabolism, 100(11), E1415-E1427 (2015-08-26)
Activin A increases matrix metalloproteinase (MMP) 2 expression and cell invasion in human trophoblasts, but whether the expression of MMP2 is essential for the proinvasive effect of activin A has yet to be determined. Moreover, the identity of the activin
Hannah E J Yong et al.
Pregnancy hypertension, 5(4), 346-353 (2015-11-26)
Activin A, a TGFβ family member, circulates in the maternal blood at increasing concentrations throughout gestation during a healthy pregnancy. The circulating concentration of activin A is further increased in pre-eclampsia (PE), a hypertensive disorder of pregnancy that is marked
Melissa L Brown et al.
Islets, 6(5-6), e1017226-e1017226 (2015-04-04)
Emerging evidence suggests that activin with its associated receptors, second messengers, and antagonists would be excellent targets for therapeutic drug development in the treatment of diabetes. We undertook the current study to investigate the ability to extrapolate findings from rodent
Xu Qian et al.
Biomaterials, 35(36), 9581-9590 (2014-09-06)
Well-defined culture conditions are essential for realizing the full potential of human embryonic stem cells (hESCs) in regenerative medicine where large numbers of cells are required. Synthetic polymers such as poly[2-(methacryloyloxy) ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] (PMEDSAH), offer multiple advantages over
Hsun-Ming Chang et al.
Molecular and cellular endocrinology, 412, 290-301 (2015-05-24)
Activins are homo- or heterodimers of inhibin β subunits that play important roles in the reproductive system. Our previous work has shown that activins A (βAβA), B (βBβB) and AB (βAβB) induce aromatase/estradiol, but suppress StAR/progesterone production in human granulosa-lutein
Exibir todos os documentos relacionados

Artigos

Growth Factors in Stem Cell Biology

Role of growth factors in stem cell differentiation and various growth factors for your research at sigmaaldrich.com

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica