SML3391

Glatiramer acetate

≥95% (HPLC)

• Sinônimo(s): Cop 1 (polyamide), Cop-1, Copaxone, Copolymer 1, GA, Polymer with L-alanine, L-lysine, L-tyrosine, and L-glutamic acid acetate
• Fórmula linear: (C₉H₁₁NO₃)_a·(C₆H₁₄N₂O₂)_b ·(C₅H₉NO₄)_c ·(C₃H₇NO₂)_d ·x(CH₃CO₂H)
• Código UNSPSC: 12352200
• NACRES: NA.21

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• Formulário: (Powder or Lyophilized powder or film)
• condição de armazenamento: desiccated
• cor: white to beige
• temperatura de armazenamento: -10 to -25°C
• cadeia de caracteres SMILES: OC([C@@H](N)C)=O.OC(CC[C@H](N)C(O)=O)=O.NCCCC[C@H](N)C(O)=O.OC([C@@H](N)CC1=CC=C(C=C1)O)=O
• InChI: 1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1
• chave InChI: YLOCGHYTXIINAI-XKUOMLDTSA-N

Descrição

Ações bioquímicas/fisiológicas

Glatiramer acetate, a myelin basic protein mimetic, is an immunomodulator used for treatment of Multiple Sclerosis. Glatiramer acetate is a mixture of synthetic peptides randomly composed of glutamic acid, lysine, alanine, and tyrosine. It reduces relapse rate and disease progression in Multiple Sclerosis. Its mechanism of action is not fully understood. Glatiramer acetate generates anti-inflammatory Th2 cells, which produce neurotrophic factors.

Myelin basic protein mimetic; immunodmodulator; used to treat multiple sclerosis; generates anti-inflammatory Th2 cells, which produce neurotrophic factors; promotes neurogenesis

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable