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SML0054

Sigma-Aldrich

Schizandrin

≥98% (HPLC)

Sinônimo(s):

(+)-Schizandrin, Schisandrin, Schisandrine, Wuweizi alcohol A, Wuweizichun A

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About This Item

Fórmula empírica (Notação de Hill):
C24H32O7
Número CAS:
7432-28-2
Peso molecular:
432.51
Número MDL:
MFCD00905761
Código UNSPSC:
12352200
ID de substância PubChem:
329825121
NACRES:
NA.77

Ensaio

≥98% (HPLC)

forma

powder

atividade óptica

[α]/D 75 to 95°, c = 1 in methanol

cor

white to beige

solubilidade

DMSO: ≥13 mg/mL

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC

InChI

1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1

chave InChI

YEFOAORQXAOVJQ-RZFZLAGVSA-N

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Aplicação

Schizandrin may be used in oxidative stress-related cell signaling studies.

Ações bioquímicas/fisiológicas

Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin has been reported to have hepatoprotective, antitumor, antiviral, and antiamnesic effects, and has neuroprotective activity against glutamate induced neurotoxicity.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Shih-Hung Yang et al.
Journal of the science of food and agriculture, 91(4), 694-702 (2011-02-09)
Schisandra chinensis, commonly used in Asia for tea material and traditional Chinese medicine, is presumed to enhance mental and intellectual functions. In this study, the effects and signalling mechanisms of a purified compound schisandrin, one of the lignan of Schisandra
Si-Yuan Pan et al.
Lipids in health and disease, 11, 120-120 (2012-09-20)
Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic extracts (AqFSC, EtFSC), on serum/hepatic lipid contents in normal diet
Bing Shao et al.
Drug development and industrial pharmacy, 36(11), 1356-1363 (2010-09-21)
Wurenchun is the alcohol extract from Fructus Schisandrae Chinensis, which has good efficiency in lowering abnormal serum glutamic pyruvic transaminase (SGPT) level of patients suffering from acute or chronic hepatitis. The main purpose of this work is to prepare self-emulsifying
Jia-Ming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(13), 1153-1160 (2011-07-19)
In this study, the herbal extracts of Schisandra chinensis were demonstrated to inhibit the contractions induced by acetylcholine (ACh) and serotonin (5-HT) in guinea pig ileum, and the 95% ethanol extract was more effective than the aqueous extract. Analysis with
Sun Young Park et al.
Immunology letters, 139(1-2), 93-101 (2011-06-08)
The lipopolysaccharide (LPS) of Porphyromonas gingivalis is thought to induce periodontitis. In this study, we isolated Schisandrin from the dried fruits of Schisandra chinensis and examined the anti-inflammatory effect of Schisandrin in macrophages stimulated with LPS from P. gingivalis. First
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