SML0014

Scutellarin hydrate

≥98% (HPLC)

• Sinônimo(s): 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• Fórmula empírica (Notação de Hill): C₂₁H₁₈O₁₂ · xH₂O
• Número CAS: 27740-01-8
• Peso molecular: 462.36 (anhydrous basis)
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• forma: powder
• condição de armazenamento: desiccated
• cor: yellow
• solubilidade: DMSO: ≥10 mg/mL
• temperatura de armazenamento: 2-8°C

Descrição

Aplicação

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

Ações bioquímicas/fisiológicas

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Características e benefícios

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable