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SMB00705

Sigma-Aldrich

Sesamin

≥98% (HPLC)

Sinônimo(s):

Fagarol

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About This Item

Fórmula empírica (Notação de Hill):
C20H18O6
Número CAS:
607-80-7
Peso molecular:
354.35
Número MDL:
MFCD00216134
Código UNSPSC:
12352205
NACRES:
NA.25
Preço e disponibilidade não estão disponíveis no momento.

Nível de qualidade

200

Ensaio

≥98% (HPLC)

Formulário

powder

solubilidade

DMSO: 10 mg/mL

aplicação(ões)

metabolomics
vitamins, nutraceuticals, and natural products

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5

InChI

1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

chave InChI

PEYUIKBAABKQKQ-AFHBHXEDSA-N

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Descrição geral

Sesamin is the most abundant lignan isolated from Sesamum indicum or sesame seeds and sesame oil.

Aplicação

Sesamin has been used as a reference standard to study the activity of Cytochrome P450 enzyme sesamin synthase from Sesamum indicum L. in the conversion of pinoresinol to sesamin.

Ações bioquímicas/fisiológicas

Non-competitive Δ5-desaturase inhibitor.
Sesamin presents multiple health benefits including hypocholesterolemic, anti-hypertensive, anti-carcinogenic, anti-aging, immunoregulatory, hypoglycemic, anti-thrombotic, hepatoprotective, and antioxidant activities.[1] It has also been demonstrated to work synergistically with vitamin E against lipid peroxidation.[1] Sesamin was found to be metabolized into several catechol forms in the liver.[2] These cathecols have a potent ability to scavenge superoxide radicals.[3]

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H317

Classificações de perigo

Skin Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
0000400766
0000380339
0000380339
0000400766
0000232685

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Formiato de amônio reagent grade, 97%

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Colonoscope constriction and laser safety interlock problems investigated.
Today's OR nurse, 14(3), 48-48 (1992-03-01)
Mitsuo Namiki
Critical reviews in food science and nutrition, 47(7), 651-673 (2007-10-19)
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve
Sarah Dalibalta et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(10), 1276-1289 (2020-11-03)
Sesamin, a major lignin isolated from sesame (Sesamum indicum) seeds and sesame oil, is known to possess antioxidant and anti-inflammatory properties. Several studies have revealed that oxidative stress and inflammation play a major role in a variety of cardiovascular diseases
Yun-Ping Lim et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 242810-242810 (2012-05-31)
Inconsistent expression and regulation of drug-metabolizing enzymes (DMEs) are common causes of adverse drug effects in some drugs with a narrow therapeutic index (TI). An important cytochrome, cytochrome P450 3A4 (CYP3A4), is predominantly regulated by a nuclear receptor, pregnane X
W C Johnson et al.
Life sciences, 51(15), 1229-1236 (1992-01-01)
A two step fractionation of conditioned media made from the darkly pigmented dorsal skin of the channel catfish, Ictalurus punctatus, has produced fractions that contain a melanization stimulating factor (MSF). Isolated neural tubes of Xenopus laevis embryos exposed to conditioned
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