SAB5500134
Anti-KI-67 antibody, Rabbit monoclonal
recombinant, expressed in proprietary host, clone SP6, tissue culture supernatant
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100 μL
R$ 1.431,00
R$ 1.431,00
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100 μL
R$ 1.431,00
About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
R$ 1.431,00
Check Cart for Availability
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
recombinante
expressed in proprietary host
conjugado
unconjugated
forma do anticorpo
tissue culture supernatant
tipo de produto de anticorpo
primary antibodies
clone
SP6, monoclonal
reatividade de espécies
human (tested)
reatividade da espécie (prevista por homologia)
bovine
técnica(s)
immunohistochemistry: 1:200
Isotipo
IgG
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... MKI67(4288)
Descrição geral
Ki-67 is a nuclear protein, which is expressed in the proliferating cells. Ki-67 is preferentially expressed during late G1-, S-, M-, and G2-phases of the cell cycle, while cells in the G0 (quiescent) phase are negative for this protein.
The gene marker of proliferation Ki-67 (MKI67), spanning 15 exons, is mapped to human chromosome 10q26.2. The encoded protein contains phosphopeptide-binding forkhead-associated (FHA) domain and a protein phosphatase 1 (PP1)-binding site at N- terminal. It possesses 16 tandem repeats at central region and leucine and arginine (LR) pairs at C- terminal end.
Imunogênio
Synthetic peptide from C-terminus of human Ki-67 protein.
Aplicação
Anti-KI-67 antibody, Rabbit monoclonal has been used in immunohistochemistry.
Ações bioquímicas/fisiológicas
Marker of proliferation Ki-67 (MKI67), which is a part of the mitotic chromosome periphery, functions as a biological surfactant to maintain individual mitotic chromosomes dispersed in the cytoplasm after nuclear envelope disassembly. Ki-67 is a vital prognostic marker in breast and prostate cancer. Expression of the encoded protein is associated with cell-proliferation rate. Ki-67 is expressed at all active phases of the cell cycle (G (1), S, G (2), and mitosis), except resting cells (G (0)). Therefore, this protein is considered to be a potent cell proliferation marker.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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