SAB4504450

Anti-phospho-SAPK/JNK (pTyr¹⁸⁵) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-JNK, Anti-JNK-46, Anti-JNK1, Anti-JNK1A2, Anti-JNK21B1/2, Anti-PRKM8, Anti-SAPK1, Anti-SAPK1c
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 48 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P45983; P45984; P53779
• nº de adesão UniProt: P45983
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr185)
• Informações sobre genes: human ... MAPK10(5602) , MAPK8(5599) , MAPK9(5601)

Descrição

Descrição geral

MAPK9 (mitogen-activated protein kinase 9)/JNK2 (C-Jun N-terminal kinase 2)/ stress-activated protein kinase 2 (SAPK2) spans around 58494bp. The JNK2 gene is located on human chromosome 5q35. It has 17 introns.

Imunogênio

The antiserum was produced against synthesized peptide derived from human SAPK/JNK around the phosphorylation site of Tyr185.

Immunogen Range: 151-200

Ações bioquímicas/fisiológicas

Stress-activated protein kinase 2 (SAPK2) participates in proliferation, differentiation, apoptosis, migration, transcriptional regulation and development. It controls the cellular acidic/lysosomal cellular compartment. JNK2 plays an important role in mediating stress-induced apoptosis and modulating gene expression.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable