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Documentos Principais

SAB4503944

Sigma-Aldrich

Anti-phospho-MYPT1 (pThr853) antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-phospho-MYPT1, Phospho-MYPT1 Detection, Rabbit Anti-MYPT1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

antigen 115 kDa

reatividade de espécies

human, mouse, rat

concentração

~1 mg/mL

técnica(s)

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

nº de adesão NCBI

O14974

nº de adesão UniProt

O14974

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

phosphorylation (pThr853)

Informações sobre genes

human ... PPP1R12A(4659)

Imunogênio

The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853.

Immunogen Range: 621-670

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
109170518
110518

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Pharmaceuticals (Basel, Switzerland), 16(8) (2023-08-26)
The Rho associated coiled-coil containing protein kinase (ROCK1 and ROCK2) and myotonic dystrophy-related Cdc-42 binding kinases (MRCKα and MRCKβ) are critical regulators of cell proliferation and cell plasticity, a process intimately involved in cancer cell migration and invasion. Previously, we
Feng Liu et al.
Kidney & blood pressure research, 43(5), 1425-1436 (2018-09-14)
Endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells (GEnCs) can induce albuminuria in diabetic nephropathy. Melatonin attenuates diabetic nephropathy, but its role and mechanism in EndMT of GEnCs in diabetic nephropathy remain unknown. The effect of melatonin on EndMT induced by
Gui Hua Wang et al.
Biochemical and biophysical research communications, 509(2), 596-602 (2019-01-05)
Platelet microparticles (PMPs) are closely associated with diabetic macrovascular complications. This study aimed to explore the underlying mechanisms of high glucose-induced PMPs generation. Washed platelets, obtained from the plasma of healthy male Sprague-Dawley rats, were incubated with high glucose. PMPs
Yonglin Yu et al.
Colloids and surfaces. B, Biointerfaces, 170, 1-10 (2018-06-03)
Titanium substrates with micro/nano hierarchical features could positively mediate the osteogenesis of a titanium implant; nevertheless, the underlying molecular mechanism needs to be further revealed. In this work, we fabricated a micro/nano hierarchically structured Ti (MNT) sample and attempted to
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