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SAB4200680

Sigma-Aldrich

Anti-Biotin antibody, Mouse monoclonal

clone BN-34, purified from hybridoma cell culture

Sinônimo(s):

Monoclonal Anti-Biotin antibody produced in mouse, Bios II, Coenzyme R, D-Biotin, Vitamin B7, Vitamin H

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100 μL
R$ 3.868,00

R$ 3.868,00

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R$ 3.868,00

About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

R$ 3.868,00

Check Cart for Availability
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fonte biológica

mouse

Nível de qualidade

200

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

BN-34, monoclonal

Formulário

buffered aqueous solution

reatividade de espécies

canine, human, bovine, rat, mouse

concentração

~1 mg/mL

técnica(s)

ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: 0.15-0.3 μg/mL
western blot: suitable

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Descrição geral

Biotin is a bi-heterocyclic, essential water soluble vitamin and a cofactor synthesized in most of the plants and prokaryotes. Protein-bound biotin in usually found in dietary sources like meat, cereals, egg yolk, liver and some vegetables.

Imunogênio

biotinylated KLH

Ações bioquímicas/fisiológicas

Biotin functions as a coenzyme for acetyl CoA, pyruvate, propionyl-CoA and 3-methylcrotonyl-CoA carboxylases for the regulation of gluconeogenesis, lipid homeostasis, pleotropic gene expression and to replenish the intermediates of tricarboxylic cycle. Biotin bound to histones plays an important role in chromatin remodeling, DNA repair and repression of transposons to maintain genome stability. Inadequate biotin levels may lead to dermatitis, conjunctivitis, alopecia, and central nervous system abnormalities.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
0000412735
0000412735
0000381740
0000381740
0000312696

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Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1-4, label-free single-molecule analysis5-14 and nanomedicine5. Transport traditionally relies on barrel-like channels of a few nanometres width, but there is considerable scientific and technological interest for much wider structures
Molecular biology of biotin attachment to proteins
Chapman-Smith Anne and Cronan Jr JE
The Journal of Nutrition, 129(2), 477S-484S (1999)
Abigail M Wojtowicz et al.
Biomaterials, 31(9), 2574-2582 (2010-01-09)
Healing large bone defects and non-unions remains a significant clinical problem. Current treatments, consisting of auto and allografts, are limited by donor supply and morbidity, insufficient bioactivity and risk of infection. Biotherapeutics, including cells, genes and proteins, represent promising alternative
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PloS one, 11(6), e0156718-e0156718 (2016-06-02)
Ubiquitination is a key post-translational modification in the regulation of numerous biological processes in eukaryotes. The primary roles of ubiquitination are thought to be the triggering of protein degradation and the regulation of signal transduction. During protein ubiquitination, substrate specificity
Michael Reinartz et al.
The Journal of biological chemistry, 283(25), 17440-17449 (2008-04-23)
Nitric oxide (NO) is produced by different isoforms of nitric oxide synthases (NOSs) and operates as a mediator of important cell signaling pathways, such as the cGMP signaling cascade. Another mechanism by which NO exerts biological effects is mediated through
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