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S8192

Sigma-Aldrich

Anti-phospho-Synapsin I (pSer603) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

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About This Item

Número MDL:
MFCD03792019
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

mouse, Xenopus, bovine, human, zebrafish, rat

concentração

~1 mg/mL

técnica(s)

western blot: 1:1,000 using rat brain hipoccampal tissue homogenate

nº de adesão UniProt

P17600

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

phosphorylation (pSer603)

Informações sobre genes

human ... SYN1(6853)
mouse ... Syn1(20964)
rat ... Syn1(24949)

Imunogênio

synthetic phosphorylated peptide derived from the region of rat synapsin I that is phosphorylated on serine 603.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

forma física

Solution in 10 mM HEPES buffer, pH 7.5, and 150 mM NaCl containing 100 μg/ml bovine serum albumin and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Heather D VanGuilder et al.
The European journal of neuroscience, 28(1), 1-11 (2008-07-30)
Diabetic retinopathy can result in vision loss and involves progressive neurovascular degeneration of the retina. This study tested the hypothesis that diabetes decreases the retinal expression of presynaptic proteins involved in synaptic function. The protein and mRNA contents for synapsin
Jing Zhang et al.
Journal of neuroendocrinology, 25(8), 753-761 (2013-05-18)
Hypothalamic glutamate (Glu) and γ-GABA neurotransmission are involved in the ovarian hormone-induced gonadotrophin-releasing hormone (GnRH)/luteinising hormone (LH) surge in rodents. Studies have shown that reduced Glu and increased γ-GABA in the rostral preoptic area (rPOA) of the hypothalamus, where most
Zhenxia Qin et al.
PloS one, 8(11), e80758-e80758 (2013-11-14)
Isoaspartate (isoAsp) formation is a major source of protein damage that is kept in check by the repair function of protein L-isoaspartyl methyltransferase (PIMT). Mice deficient in PIMT accumulate isoAsp-containing proteins, resulting in cognitive deficits, abnormal neuronal physiology and cytoarchitecture
Dillon Y Chen et al.
Nature neuroscience, 15(12), 1707-1714 (2012-11-20)
Emotionally important events are well remembered. Although memories of emotional experiences are known to be mediated and modulated by stress hormones such as glucocorticoids, little is known about the underlying molecular mechanisms. We found that the hippocampal glucocorticoid receptors that

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