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S3388

Sigma-Aldrich

Sulforhodamine 101 acid chloride

Technical grade

Sinônimo(s):

Sulforhodamine 101 sulfonyl chloride

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About This Item

Fórmula empírica (Notação de Hill):
C31H29ClN2O6S2
Número CAS:
82354-19-6
Peso molecular:
625.15
Beilstein:
8667894
Número MDL:
MFCD00012406
Código UNSPSC:
12171500
ID de substância PubChem:
24899558
NACRES:
NA.47

forma

powder

composição

Dye content, ~75%

Impurezas

~1 mol/mol chloroform as solvent of crystallization

solubilidade

methanol: 10 mg/mL

fluorescência

λex 586 nm; λem 605 nm in H2O

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

chave InChI

MPLHNVLQVRSVEE-UHFFFAOYSA-N

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Descrição geral

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine. The dye can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Aplicação

Sulforhodamine 101 acid chloride has been used in an encapsulated fluorescent probe as a model drug to study drug-delivery properties of rhamnogalacturonan-I based microcapsules. It has also been used in confocal imaging as an astrocyte specific dye.

Ligação

Mixture of the two monosulfonyl chloride derivatives of sulforhodamine 101.

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palavra indicadora

Danger

Classificações de perigo

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

A2348

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6-Carboxy-tetramethylrhodamine N-succinimidyl ester BioReagent, suitable for fluorescence

Sigma-Aldrich

88997

6-Carboxy-tetramethylrhodamine N-succinimidyl ester

In vivo imaging of oligodendrocytes with sulforhodamine 101
Robert A Hill
Nature Medicine, 11(11), 1081-1082 (2014)
Ping-Jung Su et al.
Biomacromolecules, 13(9), 2917-2925 (2012-08-11)
To understand complex micro/nanoscale ECM stem cell interactions, reproducible in vitro models are needed that can strictly recapitulate the relative content and spatial arrangement of native tissue. Additionally, whole ECM proteins are required to most accurately reflect native binding dynamics.
Tian Wang et al.
Cell biochemistry and biophysics, 65(3), 381-398 (2012-10-31)
Loop diuretics such as bumetanide and furosemide enhance aminoglycoside ototoxicity when co-administered to patients and animal models. The underlying mechanism(s) is poorly understood. We investigated the effect of these diuretics on cellular uptake of aminoglycosides, using Texas Red-tagged gentamicin (GTTR)
Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release
Anna J
PLoS ONE, 11(12), e0168050-e0168050 (2016)
Yang Liu et al.
Pharmaceutical research, 29(12), 3273-3277 (2012-07-19)
The biodistribution of Lipid/Calcium/Phosphate (LCP) nanoparticles (NPs) in tumor-bearing mice was investigated using fluorescence imaging. A quantitative validation of this method was done by (3)H and (111)In labeling of the nanoparticles. The biodistribution of LCP NPs containing oligonucleotides was investigated
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