S3147

5-Sulfosalicylic acid dihydrate

suitable for electrophoresis, ≥99%

• Sinônimo(s): 2-Hydroxy-5-sulfobenzoic acid
• Fórmula linear: HO₃SC₆H₃-2-(OH)CO₂H·2H₂O
• Número CAS: 5965-83-3
• Peso molecular: 254.21
• Beilstein: 650741
• Número CE: 202-555-6
• Número MDL: MFCD00149540
• Código UNSPSC: 41105319
• ID de substância PubChem: 24899547
• NACRES: NB.22

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥99%
• Formulário: powder or crystals
• técnica(s): electrophoresis: suitable
• Impurezas: ≤0.02% Insoluble matter; ≤0.05% Salicylic Acid
• pf: 105-110 °C (lit.)
• solubilidade: water: soluble 100 mg/mL, clear, colorless
• traços de ânion: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.035%
• traços de cátion: Fe: ≤0.001%; heavy metals (as Pb): ≤0.002%
• cadeia de caracteres SMILES: [H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O
• InChI: 1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2
• chave InChI: BHDKTFQBRFWJKR-UHFFFAOYSA-N

Descrição

Descrição geral

5-Sulfosalicylic acid is a strong acid capable of protonating water.[1] It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS).[2] It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.[1]

Aplicação

5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC.[3] It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].[4]

Nota de análise

Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H314
• Declarações de precaução: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Classificações de perigo: Eye Dam. 1 - Skin Corr. 1B
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves