As reported in the 'DESCRIPTION' section of the product page, Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. This product has not been further characterized.
S1006
Sulfatides from bovine brain
≥97% (TLC), powder
Sinônimo(s):
Cerebroside sulfate
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R$ 4.419,00
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5 MG
R$ 4.419,00
10 MG
R$ 6.418,00
50 MG
R$ 22.057,00
About This Item
Código UNSPSC:
12352200
NACRES:
NA.77
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Descrição geral
Sulfatideis a glycospingolipid and plays an essential role in host-pathogen recognition,β-cell function, infection, haemostasis/thrombosis, protein trafficking, cellgrowth, cell adhesion, neuronal plasticity, cell morphogenesis, and signaltransduction.[1][2] It is found on the surface of the blood cells such asplatelets, leukocytes, and erythrocytes. Sulfatides are also found in the serumas glycosphingolipids in lipoproteins.[3] It is made up of glycan part, a hydrophobic part, 3-O-sulfated galactose, and ceramide, which in turn is composed of a sphingosine base and a fatty acid.[1] It is an important component forthe maintenance of the myelin sheath andproper formation of the axo-glial junctions. Variations in the production ofsulfatides are associated with various human diseases like cancer andimmunological disorders. Alterations in the sulfatide metabolism lead to synapticdysfunction, neurological decline, inflammation, and myelin deterioration.[1]
Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. It is localized in myelin sheath and comprises approximately 4% of total myelin lipid in brain.[4]
Aplicação
Ações bioquímicas/fisiológicas
Sulfatides play a key role in physiological processes of nervous system, immune system and in insulin secretion.[4] Anomalies in sulfatides catabolism in lysosome is implicated in late infantile metachromatic leukodystrophy.[8] High levels of sulfatides is also observed in ovarian cancer.[9] Sulfatides contribute to the pathogenesis of chronic inflammatory diseases of the central nervous system.[10]
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Age-and brain region-specific effects of dietary vitamin K on myelin sulfatides
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Sulfatide (3-O-sulfogalactosylceramide, SM4) is a glycosphingolipid, highly multifunctional and particularly enriched in the myelin sheath of neurons. The role of sulfatide has been implicated in various biological fields such as the nervous system, immune system, host-pathogen recognition and infection, beta
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Artigos
Discover Bioactive Small Molecules for Lipid Signaling Research
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