PZ0015

Trovafloxacin mesylate

>98% (HPLC), powder, Pannexin 1 inhibitor

• Sinônimo(s): (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate
• Fórmula empírica (Notação de Hill): C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
• Número CAS: 147059-75-4
• Peso molecular: 512.46
• Número MDL: MFCD00913361
• Código UNSPSC: 12352200
• ID de substância PubChem: 329823684
• NACRES: NA.77

Propriedades

• Nome do produto: Trovafloxacin mesylate, >98% (HPLC)
• Ensaio: >98% (HPLC)
• Formulário: powder
• cor: white to off-white
• solubilidade: DMSO: >10 mg/mL
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F
• InChI: 1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;
• chave InChI: DYNZICQDCVYXFW-AHZSKCOESA-N

Descrição

Aplicação

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures.[1] It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.[2]

Ações bioquímicas/fisiológicas

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.[2]

Trovafloxacin mesylate is a broad spectrum antibiotic.

Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

Informações de segurança

• Pictogramas: GHS08,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H314,H361
• Declarações de precaução: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Repr. 2 - Skin Corr. 1B
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable