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P7505

Sigma-Aldrich

Putrescine dihydrochloride

≥98% (TLC), powder

Sinônimo(s):

1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride

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About This Item

Fórmula linear:
NH2(CH2)4NH2 · 2HCl
Número CAS:
333-93-7
Peso molecular:
161.07
Beilstein:
3906680
Número CE:
206-375-9
Número MDL:
MFCD00012526
Código UNSPSC:
12352200
ID de substância PubChem:
24278650
NACRES:
NA.77

product name

Putrescine dihydrochloride, ≥98% (TLC)

Ensaio

≥98% (TLC)

forma

powder

pf

280 °C (dec.) (lit.)

solubilidade

H2O: soluble 100 mg/mL, clear, colorless

cadeia de caracteres SMILES

Cl[H].Cl[H].NCCCCN

InChI

1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H

chave InChI

XXWCODXIQWIHQN-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação

Putrescine dihydrochloride has been used:
  • as a bioactive amine standard in high-performance liquid chromatography (HPLC)
  • as a component of hormone mix supplemented to Dulbecco′s modified eagle medium (DMEM) to study its effects on neural stem cells
  • as a supplement in DMEM for culturing of endometrial cancer cells

Ações bioquímicas/fisiológicas

Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
Putrescine is an aliphatic amine and is positively charged. It acts as a precursor of spermine and plays a role in polyamine biosynthesis. Putrescine is found in several plants, animals, and bacteria. It plays a role in cell proliferation and cell growth in Escherichia coli. Putrescine is a component of agrochemicals, surfactants, pharmaceuticals, polymers, and additives.

Pictogramas

Skull and crossbonesCorrosion
GHS06,GHS05

Palavra indicadora

Danger

Frases de perigo

H302,H311,H314,H330

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

113.0 °F - closed cup

Ponto de fulgor (°C)

45 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

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Bangmin Liu et al.
Journal of animal science and biotechnology, 10, 69-69 (2019-09-14)
Polyamines are essential for cell growth and beneficial for intestinal maturation. To evaluate the effects of putrescine on alleviating intestinal atrophy and underlying molecular mechanisms, both in vivo feeding trial and in vitro cell culture were conducted. Weanling pigs were
Ulises Gómez-Pinedo et al.
Frontiers in neurology, 8, 255-255 (2017-06-22)
Alexander disease (AxD) is a rare disease caused by mutations in the gene encoding glial fibrillary acidic protein (GFAP). The disease is characterized by presence of GFAP aggregates in the cytoplasm of astrocytes and loss of myelin. Determine the effect
Mito Kanatsu-Shinohara et al.
Methods in enzymology, 477, 17-36 (2010-08-12)
Spermatogonial stem cells (SSCs) in the testes are a new target for germline modification. With the development of an in vitro culture system and spermatogonial transplantation technique, SSCs can now be manipulated and used as an alternative to embryonic stem
Zhi-Gang Qian et al.
Biotechnology and bioengineering, 104(4), 651-662 (2009-08-29)
A four carbon linear chain diamine, putrescine (1,4-diaminobutane), is an important platform chemical having a wide range of applications in chemical industry. Biotechnological production of putrescine from renewable feedstock is a promising alternative to the chemical synthesis that originates from
Vegetables consumed in Brazilian cuisine as sources of bioactive amines
Dala-Paula B M, et al.
Food Bioscience, 40, 100856-100856 (2021)
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