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M6546

Sigma-Aldrich

(±)-2-(p-Methoxyphenoxy)propionic acid

solid, ≥98%

Sinônimo(s):

PMP

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About This Item

Fórmula empírica (Notação de Hill):
C10H12O4
Número CAS:
13794-15-5
Peso molecular:
196.20
Número MDL:
MFCD01310545
Código UNSPSC:
12352202
ID de substância PubChem:
24897095
NACRES:
NA.77

product name

(±)-2-(p-Methoxyphenoxy)propionic acid, ≥98%

fonte biológica

synthetic (organic)

Ensaio

≥98%

forma

solid

cadeia de caracteres SMILES

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

chave InChI

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Aplicação

(±)-2-(p-Methoxyphenoxy)propionic acid may be used as a sweet taste receptor antagonist to study its effect on allulose-induced glucagon-like peptide 1 (GLP-1) secretion rats. It may also be used to study the response of the secretin tumor cell line (STC-1) to sweetener in the presence and absence of (±)-2-(p-methoxyphenoxy)propionic acid or lactisole.

Ações bioquímicas/fisiológicas

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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A Sclafani et al.
Physiology & behavior, 61(1), 25-29 (1997-01-01)
Cypha, propionic acid, 2-(4-methoxyphenol) salt, is a commercially available sweet taste inhibitor used in food products. The present study examined whether or not Cypha blocked the sweet taste response of rats. This was accomplished by measuring the consummatory response of
David E Lanfear et al.
JACC. Heart failure, 5(11), 823-832 (2017-11-04)
This study sought to derive and validate plasma metabolite associations with survival in heart failure (HF) patients. Profiling of plasma metabolites to predict the course of HF appears promising, but validation and incremental value of these profiles are less established. Patients
Paolo Tommasino et al.
Frontiers in neurorobotics, 11, 65-65 (2017-12-19)
A major challenge in robotics and computational neuroscience is relative to the posture/movement problem in presence of kinematic redundancy. We recently addressed this issue using a principled approach which, in conjunction with nonlinear inverse optimization, allowed capturing postural strategies such
Li-Chun Chen et al.
Food chemistry, 212, 768-777 (2016-07-05)
The biological functions of cell membranes strongly influence the binding and transport of molecular species. We developed STC-1 cell line stably expressing the sweet taste receptor (T1R2/T1R3), and explored the possible correlation between sweeteners and membrane dipole potential of STC-1
Lilli Saarinen et al.
PloS one, 12(4), e0174898-e0174898 (2017-04-21)
Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal
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