M1568

Mannose triflate

For PET imaging, ≥98% (TLC)

• Sinônimo(s): β-D-Mannopyranose 1,3,4,6-tetra-O-acetate 2-O-trifluoromethanesulfonate, 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose, Mannose triflate, TATM
• Fórmula empírica (Notação de Hill): C₁₅H₁₉F₃O₁₂S
• Número CAS: 92051-23-5
• Peso molecular: 480.36
• Beilstein: 4341413
• Número MDL: MFCD00012353
• Código UNSPSC: 41116107
• ID de substância PubChem: 24896669
• NACRES: NA.12

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥98% (TLC)
• técnica(s): PET imaging: suitable
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
• InChI: 1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1
• chave InChI: OIBDVHSTOUGZTJ-PEBLQZBPSA-N

Descrição

Descrição geral

Mannose triflate is a glucose analogue.

Aplicação

Mannose triflate is a well-known precursor for ¹⁸F-FDG synthesis for PET applications. The binding of ¹⁸F to the mannose triflate has been carried out via SN₂ nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

Outras notas

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)