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L9037

Sigma-Aldrich

L-Lysine monohydrate

98.5-101.5% dry basis, suitable for cell culture, BioReagent, non-animal source

Sinônimo(s):

L-Lysine hydrate (1:1), Lysine monohydrate

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About This Item

Fórmula empírica (Notação de Hill):
C6H14N2O2 · H2O
Número CAS:
39665-12-8
Peso molecular:
164.20
Beilstein:
4349963
Número CE:
200-294-2
Número MDL:
MFCD00151035
Código UNSPSC:
12352209
ID de substância PubChem:
24896515
NACRES:
NA.26

product name

L-Lysine monohydrate, BioReagent, suitable for cell culture, from non-animal source

fonte biológica

non-animal source

linha de produto

BioReagent

Ensaio

98.5-101.5% dry basis

forma

crystalline powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

cor

white

pf

215 °C

solubilidade

H2O: soluble

cadeia de caracteres SMILES

[H]O[H].NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1

chave InChI

HZRUTVAFDWTKGD-JEDNCBNOSA-N

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Descrição geral

L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.

Aplicação

L-Lysine monohydrate has been used in:
  • SILAC (stable isotope labeling by amino acids in cell culture) method
  • the complete synthetic (C) medium for positive selection screening of yeast cells
  • the growth medium for cells

Ações bioquímicas/fisiológicas

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
Shao-En Ong et al.
Nature protocols, 1(6), 2650-2660 (2007-04-05)
Stable isotope labeling by amino acids in cell culture (SILAC) is a simple, robust, yet powerful approach in mass spectrometry (MS)-based quantitative proteomics. SILAC labels cellular proteomes through normal metabolic processes, incorporating non-radioactive, stable isotope-containing amino acids in newly synthesized
Daniel Kalb et al.
Chembiochem : a European journal of chemical biology, 16(10), 1426-1430 (2015-05-13)
L-α-Aminoadipic acid reductases catalyze the ATP- and NADPH-dependent reduction of L-α-aminoadipic acid to the corresponding 6-semialdehyde during fungal L-lysine biosynthesis. These reductases resemble peptide synthetases with regard to their multidomain composition but feature a unique domain of elusive function--now referred
W L McKeehan et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(6), 2023-2027 (1976-06-01)
The trace element selenium is essential for clonal growth of diploid fibroblasts from human fetal lung (WI-38) in media containing small amounts of serum protein. Maximum growth stimulation is obtained when 30 nM neutralized selenious acid is added to a
Garrett RH and Grisham CM
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