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GW22489

Sigma-Aldrich

Anti-GNAI3 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-87U6, Anti-ARCND1, Anti-HG1A

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

chicken

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

human, mouse, rat

fabricante/nome comercial

Genway 15-288-22489

técnica(s)

immunocytochemistry: suitable
western blot: suitable

nº de adesão NCBI

NP_006487.1

nº de adesão UniProt

P08754

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... GNAI3(2773)

Imunogênio

Immunogen Sequence: GI # 5729850, sequence 345-353
Synthetic peptide sequence of guanine nucleotide binding protein (G protein), α inhibiting activity polypeptide 3.

Aplicação

Anti-GNAI3 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Ações bioquímicas/fisiológicas

Guanine nucleotide-binding protein G(k) subunit α is a protein encoded by the GNAI3 gene in humans. It is composed of α, β and γ subunits and mediates hormonal regulation of many membrane functions. GNAI3 subunit translocations to the cytoskeleton and its simultaneous inhibition indicates that the cytoskeleton might participate in the signaling process of human epithelial cells.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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S Y Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(12), 4153-4157 (1988-06-01)
The guanine nucleotide-binding proteins (G proteins), which mediate hormonal regulation of many membrane functions, are composed of alpha, beta, and gamma subunits. We have cloned and characterized cDNA from a human T-cell library encoding a form of alpha i that
Anil Akturk et al.
Science advances, 8(42), eabq2826-eabq2826 (2022-10-20)
Inhibitory G proteins (GNAI/Gαi) bind to the scaffold G protein signaling modulator 2 (GPSM2) to form a conserved polarity complex that regulates cytoskeleton organization. GPSM2 keeps GNAI in a guanosine diphosphate (GDP)-bound state, but how GPSM2-GNAI is generated or relates
J L Adolfsson et al.
Biochemical and biophysical research communications, 226(2), 413-419 (1996-09-13)
The present results show that stimulation of Intestine 407 epithelial cells with LTD4 (Leukotriene D4) triggers a rapid activation of the pertussis-toxin-sensitive Gi3-protein and a simultaneous translocation of its alpha-subunits to a crude cytoskeletal fraction. The activation of G alpha
Katie S Kindt et al.
Nature communications, 12(1), 2861-2861 (2021-05-19)
Hair cells detect sound, head position or water movements when their mechanosensory hair bundle is deflected. Each hair bundle has an asymmetric architecture that restricts stimulus detection to a single axis. Coordinated hair cell orientations within sensory epithelia further tune

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