Enalapril is an angiotensin-converting enzyme inhibitor. It is used to treat heart failure and high blood pressure.[1]
Aplicação
Enalapril maleate salt has been used:
to reduce albumin excretion rate (AER) and glomerular lesions[2]
to examine the effects of enalapril pre-treatment on myocardial injury[3]
to investigate its efficacious doses and schedules for mitigation of radiation lung injury[4]
Ações bioquímicas/fisiológicas
A long-acting angiotensin-converting enzyme inhibitor.
Características e benefícios
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American journal of physiology. Renal physiology, 319(4), F697-F711 (2020-09-01)
Praliciguat, a clinical-stage soluble guanylate cyclase (sGC) stimulator, increases cGMP via the nitric oxide-sGC pathway. Praliciguat has been shown to be renoprotective in rodent models of hypertensive nephropathy and renal fibrosis. In the present study, praliciguat alone and in combination
Puromycin aminonucleoside (PA) can induce nephrotic syndrome in rats, and proteinuria is an important mediator of tubulointerstitial injury in glomerulopathy. We assumed that glomerular proteinuria may affect tubular function, such as urinary concentration, and investigated whether a urinary concentration defect
Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice
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