E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

• Sinônimo(s): (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
• Fórmula linear: (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
• Número CAS: 60-00-4
• Peso molecular: 292.24
• Beilstein: 1716295
• Número CE: 200-449-4
• Número MDL: MFCD00003541
• Código UNSPSC: 12161700
• eCl@ss: 39030907
• ID de substância PubChem: 24894634
• NACRES: NA.25

Propriedades

• grau: anhydrous
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥98.5%
• Formulário: crystalline
• adequação da reação: reagent type: chelator
• técnica(s): cell culture | mammalian: suitable
• pH: 2.5 (23 °C, 10 g/L)
• pf: 250 °C (dec.) (lit.)
• solubilidade: 3 M NaOH: 100 mg/mL
• densidade: 1.46 g/cm³ at 20 °C
• traços de cátion: C: 40.7-41.5%; N: 9.3-9.8%
• cadeia de caracteres SMILES: OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
• chave InChI: KCXVZYZYPLLWCC-UHFFFAOYSA-N

Descrição

Aplicação

Ethylenediaminetetraacetic acid has been used:

• as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
• as a medium component in the hepatic stellate cell (HSCs) culture
• as a component of homogenization buffer for protein extraction from eye tissues
• for stopping benzonase reaction in lysis buffer

Ações bioquímicas/fisiológicas

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H319
• Declarações de precaução: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classificações de perigo: Eye Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves