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D8907

Sigma-Aldrich

1,2-Dioctanoylethylene glycol

~99%

Sinônimo(s):

Ethylene glycol dioctanoate

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About This Item

Fórmula empírica (Notação de Hill):
C18H34O4
Número CAS:
Peso molecular:
314.46
Número MDL:
Código UNSPSC:
41106300
ID de substância PubChem:

Ensaio

~99%

forma

liquid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCCCCCCC(=O)OCCOC(=O)CCCCCCC

InChI

1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3

chave InChI

HTNFLUQQANUSLR-UHFFFAOYSA-N

Ações bioquímicas/fisiológicas

Potent inhibitor of sn-1,2-diacylglycerol phosphorylation in vitro.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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M Tóth et al.
Acta physiologica Hungarica, 81(4), 341-354 (1993-01-01)
Diacylglycerols (DAG) are assumed to play intracellular signal roles in rapidly growing tissues like those present in the primordial human placenta. The aim of the present study was to gain information on the capacity of DAG-kinase and CDP-choline: DAG phosphocholine
P Nasmith et al.
Biochemical and biophysical research communications, 161(1), 95-100 (1989-05-30)
The diacylglycerol kinase inhibitors, R59022 and dioctanoylethylene glycol (diC8-eg), potentiate stimulation of the respiratory burst by the chemotactic tripeptide N-formyl-methionyl-leucyl-phenylalanine (fMLP) in human neutrophils. However, in contrast to the potentiation observed in intact cells, neither R59022 nor diC8-eg enhanced the
S Bourgoin et al.
The Journal of biological chemistry, 267(17), 11908-11916 (1992-06-15)
To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanadate derivatives. Micromolar concentrations of vanadyl hydroperoxide (V(4+)-OOH) induced accumulation of tyrosine-phosphorylated proteins. Concomitantly, V(4+)-OOH or
S E Severin et al.
FEBS letters, 232(2), 286-288 (1988-05-23)
Diol lipids (dioleoyl- and dioctanoylethylene glycol) at relatively low concentrations (approximately 10 microM) were found to activate significantly protein kinase C in the presence of phosphatidylserine or phosphatidylinositol. Since diol lipids are widespread minor lipid constituents of many cells [(1974)
M Tóth
Biochimica et biophysica acta, 1210(1), 105-112 (1993-12-02)
Metabolic conversion of the synthetic DAG, dioctanoylglycerol (DOCG) into the dioctanoyl species of phosphatidic acid (PADOCG) and phosphatidylcholine (PCDOCG) in minced human primordial placenta incubated with [32P]phosphate was studied. Time-course experiments performed with 0.25 mM DOCG revealed a much higher

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