The solubility of the product is not tested as this is not a part of the product specification.
However, not the same product, but product #573109, under the same CAS number had a solubility: DMSO (<1 mg/ml).
D4071
5, 15-DPP
Sinônimo(s):
5,15-Diphenyl-21H,23H-porphine, 5,15-Diphenylporphyrin, 5,15-diphenyl-Porphine
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10 MG
R$ 763,00
50 MG
R$ 2.416,00
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10 MG
R$ 763,00
50 MG
R$ 2.416,00
About This Item
Fórmula empírica (Notação de Hill):
C32H22N4
Número CAS:
Peso molecular:
462.54
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77
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Formulário
powder
cadeia de caracteres SMILES
c1ccc(cc1)-c2c3ccc(cc4ccc([nH]4)c(-c5ccccc5)c6ccc(cc7ccc2[nH]7)n6)n3
InChI
1S/C32H22N4/c1-3-7-21(8-4-1)31-27-15-11-23(33-27)19-25-13-17-29(35-25)32(22-9-5-2-6-10-22)30-18-14-26(36-30)20-24-12-16-28(31)34-24/h1-20,33,36H/b23-19-,24-20-,25-19-,26-20-,31-27-,31-28-,32-29-,32-30-
chave InChI
FNNOEKVUXXVPAI-DUVOQLPESA-N
Aplicação
5, 15-DPP has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor:
- to analyze its effects on malignant peripheral nerve sheath tumor (MPNST) survival and proliferation[1]
- to study its effects on the thymic stromal lymphopoietin (TSLP) modulation of nometastatic gene 23-H1 (NME1 or nm23-H1) expression in human trophoblasts[2]
- to study its effects on 17β-estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced M2 polarization in human macrophages and endometrial stromal cells[3]
Ações bioquímicas/fisiológicas
5, 15-DPP is a selective STAT3 inhibitor and a selective STAT3-SH2 antagonist
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Yun Wang et al.
PloS one, 10(5), e0125559-e0125559 (2015-05-08)
The goal of this study is to elucidate the effects of 17β-estradiol and TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) on macrophage phenotypes in the endometriotic milieu. Co-culture of endometrial stromal cells (ESCs) and U937 cells (macrophage cell line) was performed to simulate the endometriotic
Ying Wang et al.
Clinical immunology (Orlando, Fla.), 143(1), 88-95 (2012-03-01)
Our previous study has demonstrated that TSLP induces the invasion of human trophoblasts and plays a role in embryo implantation. The present study is undertaken to explore the mechanism by which TSLP modulates trophoblast invasion. It was revealed that TSLP
Jody Fromm Longo et al.
Cell communication and signaling : CCS, 17(1), 74-74 (2019-07-12)
We have found that erbB receptor tyrosine kinases drive Ras hyperactivation and growth in NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However, MPNSTs variably express multiple erbB receptors with distinct functional characteristics and it is not clear which of these
Shaoxue Zeng et al.
Theranostics, 12(15), 6705-6722 (2022-10-04)
Rationale: Müller cells play an essential role in maintaining the health of retinal photoreceptors. Dysfunction of stressed Müller cells often results in photoreceptor degeneration. However, how these cells communicate under stress and the signalling pathways involved remain unclear. In this
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In which solvents is 5,15 DPP dissolved?
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