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C8661

Sigma-Aldrich

Cobalt(II) chloride hexahydrate

BioReagent, suitable for cell culture, suitable for insect cell culture

Sinônimo(s):

Cobaltous chloride hexahydrate

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25 G
R$ 235,00
100 G
R$ 676,00

R$ 235,00

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25 G
R$ 235,00
100 G
R$ 676,00

About This Item

Fórmula linear:
CoCl2 · 6H2O
Número CAS:
7791-13-1
Peso molecular:
237.93
Número CE:
231-589-4
Número MDL:
MFCD00149652
Código UNSPSC:
12352207
ID de substância PubChem:
24893093
NACRES:
NA.71
Formulário:
powder

R$ 235,00

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pressão de vapor

40 mmHg ( 0 °C)

Nível de qualidade

300

linha de produto

BioReagent

Formulário

powder

técnica(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

cadeia de caracteres SMILES

O.O.O.O.O.O.Cl[Co]Cl

InChI

1S/2ClH.Co.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

chave InChI

GFHNAMRJFCEERV-UHFFFAOYSA-L

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Aplicação

  • Synthesis, Characterization, and Biological Activities of Novel Vanadium(IV) and Cobalt(II) Complexes: Investigates the synthesis of novel cobalt(II) complexes and their potential biological applications, particularly emphasizing their bioactive properties in various cellular models (Damena T, Zeleke D, Desalegn T, et al. 2022. ACS Omega).

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Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B Inhalation - Eye Dam. 1 - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
0000357466
0000374149
0000370222
0000370224
0000368596

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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Can C8661 be used in normoxia to induce hypoxia?

    1 answer

    1. CoCl2 is generally known to replace Fe2+ that binds to prolyl hydroxylase (PHD), which degrades hypoxia-inducible factor‑1α (HIF-1a) under normoxic conditions. This binding blocks the activity of PHD and subsequently upregulates the level of HIF-1a to simulate hypoxic conditions.

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