B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• Sinônimo(s): BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• Fórmula empírica (Notação de Hill): C₂₃H₂₅N₅O₂ · HCl
• Número CAS: 913-04-2
• Peso molecular: 439.94
• Beilstein: 3823291
• Número CE: 213-015-4
• Número MDL: MFCD00038940
• Código UNSPSC: 12352204
• ID de substância PubChem: 24891699
• NACRES: NA.32

Propriedades

• Ensaio: ≥98% (TLC)
• Formulário: powder
• solubilidade: DMF: 50 mg/mL, clear, colorless to faintly yellow
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• chave InChI: BNGRKDJZQIGWQF-UHFFFAOYSA-N

Descrição

Aplicação

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin.[1] It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.[2]

Ações bioquímicas/fisiológicas

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain.[3] BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens.[4] Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.[5]

Substratos

A chromogenic substrate for trypsin.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)