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Documentos Principais

A2646

Sigma-Aldrich

D-Arginine

≥98% (TLC), suitable for ligand binding assays

Sinônimo(s):

(R)-2-Amino-5-guanidinopentanoic acid

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About This Item

Fórmula linear:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
Número CAS:
Peso molecular:
174.20
Beilstein:
1725412
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.32
Preço e disponibilidade não estão disponíveis no momento.

Nome do produto

D-Arginine, ≥98% (TLC)

Ensaio

≥98% (TLC)

Formulário

powder

técnica(s)

ligand binding assay: suitable

cor

white to off-white

pf

226 °C (dec.) (lit.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1

chave InChI

ODKSFYDXXFIFQN-SCSAIBSYSA-N

Informações sobre genes

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Descrição geral

Arginine (Arg) is a dibasic amino acid and exists as two enantiomers: D-Arg and L-Arg. D-Arg is a cationic endogenous amino acid and is found in the central nervous system.[1]

Aplicação

D-Arginine has been used:
  • as an organic substrate to study the metabolic versatility of freshwater sedimentary archaea feeding on different organic carbon sources[2]
  • to study its role in the inhibition of Pseudorabies virus (PRV) plaque formation by arginase[3]
  • as a reference standard for chromatographic separation[4]

Ações bioquímicas/fisiológicas

D-Arginine is a semi-essential amino acid that maintains cell death in the central nervous system (CNS). It may possess neuroprotective actions against glucocorticoids induced neurotoxicity in the CNS.[1]

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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L-Arginina from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

A8094

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Federica Lazzari et al.
Polymers, 12(4) (2020-04-17)
D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or
M Griselda Canteros
Drug discovery today, 19(5), 627-636 (2013-11-21)
In humans, as in other mammals, endogenous glucocorticoids (GCs) are essential for adapting to physiological life stress. They are also crucial for the healthy development of the fetus. However, when the physiological concentrations of GCs increase over a long period
Bridget E Fomenky et al.
Scientific reports, 8(1), 14147-14147 (2018-09-22)
This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a
Hsien-Chi Wang et al.
Biochemical and biophysical research communications, 334(2), 631-637 (2005-07-13)
Pseudorabies virus (PRV) is a member of Alphahepesviruses; it is an enveloped virus with a double-stranded DNA genome. Polyamines (such as spermine and spermidine) are ubiquitous in animal cells and participate in cellular proliferation and differentiation. Previous results of our
Gaëlle Coussot et al.
Astrobiology, 19(8), 1053-1062 (2019-03-01)
Antibody-based analytical instruments are under development to detect signatures of life on planetary bodies. Antibodies are molecular recognition reagents able to detect their target at sub-nanomolar concentrations, with high affinity and specificity. Studying antibody binding performances under space conditions is

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