72987

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose

≥97% (HPLC)

• Sinônimo(s): 2-NBDG, 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose
• Fórmula empírica (Notação de Hill): C₁₂H₁₄N₄O₈
• Número CAS: 186689-07-6
• Peso molecular: 342.26
• Beilstein: 7603370
• Número MDL: MFCD23135882
• Código UNSPSC: 12352108
• ID de substância PubChem: 329764517
• NACRES: NA.32

Propriedades

• fonte biológica: synthetic
• Ensaio: ≥97% (HPLC)
• forma: powder
• fluorescência: λ_ex 494 nm; λ_em 551 nm in DMSO
• aplicação(ões): cell analysis
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](Nc1ccc([N+]([O-])=O)c2nonc12)C=O
• InChI: 1S/C12H14N4O8/c17-3-6(11(20)12(21)8(19)4-18)13-5-1-2-7(16(22)23)10-9(5)14-24-15-10/h1-3,6,8,11-13,18-21H,4H2/t6-,8+,11+,12+/m0/s1
• chave InChI: QUTFFEUUGHUPQC-ILWYWAAHSA-N

Descrição

Descrição geral

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose, also known as 2-NBDG, is a fluorescent D-glucose analog. The consequent fluorescent activity is detected by flow cytometry. 2-NBDG is incubated directly with the test sample for uptake, followed by measurement.

Aplicação

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose is used as a fluorescent indicator for direct glucose uptake measurement. 2-NBDG is used as a fluorescent deoxyglucose analog to study the tumor cells. For in vivo imaging of epileptic activity experiments, 2-NBDG is used as a fluorescent deoxyglucose analog.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable