466R-1

SDHB (EP288) Rabbit Monoclonal Primary Antibody

• Sinônimo(s): Succinate dehydrogenase B
• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: EP288, monoclonal
• descrição: For In Vitro Diagnostic Use in Select Regions
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (466R-14); vial of 0.1 mL concentrate Research Use Only (466R-14-RUO); vial of 0.5 mL concentrate (466R-15); vial of 1.0 mL concentrate (466R-16); vial of 1.0 mL concentrate Research Use Only (466R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (466R-17); vial of 7.0 mL pre-dilute ready-to-use (466R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)
• fabricante/nome comercial: Cell Marque^®
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• controle: GIST
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: cytoplasmic
• Informações sobre genes: human ... SDHB(6390)

Descrição

Descrição geral

Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane.[1][2] Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.[3][4]

Qualidade

IVD

IVD

IVD

RUO

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

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Outras notas

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Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable