460R-1

Heat Shock Protein 70 (EP377) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: EP377, monoclonal
• descrição: For In Vitro Diagnostic Use in Select Regions
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (460R-14); vial of 0.1 mL concentrate Research Use Only (460R-14-RUO); vial of 0.5 mL concentrate (460R-15); vial of 1.0 mL concentrate (460R-16); vial of 1.0 mL concentrate Research Use Only (460R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (460R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (460R-17); vial of 7.0 mL pre-dilute ready-to-use (460R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (460R-18-RUO)
• fabricante/nome comercial: Cell Marque^®
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• controle: hepatocellular carcinoma
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: cytoplasmic, nuclear
• Informações sobre genes: human ... HSPA1A(3303)

Descrição

Descrição geral

The Heat Shock Protein 70 family of highly conserved chaperone proteins increase in expression upon exposure to stress factors such as temperature shock, hypoxia, oxidative stress, and pH change.[1] This promotes cell survival by repairing misfolded proteins and preventing protein aggregates, among other functions.[1] Likewise, tumor cells can use this mechanism to confer a survival advantage as demonstrated in Heat Shock Protein 70 overexpression in hepatocellular carcinoma.[2][3][4][5][1]

Qualidade

United States - IVD
European Union - IVD
Japan - RUO

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

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Outras notas

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Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2