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24368C

SAFC

Alimento avançado para CHO 1 EX-CELL®

Fabricação farmacêutica

Sinônimo(s):

EX-CELL® Advanced CHO Feed 1

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About This Item

Código UNSPSC:
12352200
NACRES:
NA.71

linha de produto

EX-CELL®

Nível de qualidade

500

forma

dry powder

técnica(s)

cell culture | mammalian: suitable (suspension)

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

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Descrição geral

EX-CELL® Advanced CHO Feed 1 (without glucose) is chemically-defined and contains no animal derived components. This feed is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Fed-batch Medium (14366C or 24366C). This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME).

Ligação

Preencha o formulário de pedido de meio avançado de batelada alimentada para CHO EX-CELL para entrar em contato com um representante da SAFC.

Quantidade

Formulated to contain 64.1 grams of powder per liter of medium.

Informações legais

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

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GHS05,GHS07

Palavra indicadora

Danger

Frases de perigo

H315,H317,H318

Classificações de perigo

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Certificados de análise (COA)

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1.02578

Cellvento® Feed-220

D-(+)-Glicose 45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

Sigma-Aldrich

G8769

D-(+)-Glicose

SAFC

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14700C

EX-CELL® CD Hydrolysate Fusion

Pao-Chun Lin et al.
mAbs, 11(5), 965-976 (2019-05-03)
Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones

Artigos

One-step Feed Optimization for Upstream Cell Culture Processes

Optimizing feed for upstream cell culture improves monoclonal antibody production, but requires balancing outcomes for both viable cell density and productivity.

Improving Fed-batch Yields in Upstream Bioprocessing

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Establishing the First GMP Guideline for Cell Culture Media

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

Ver tudo

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