Based on the information available, this version does recognize the epsilon subunit. This conclusion is drawn from the fact that the CD3 epsilon, also known as the cytoplasmic CD3 antibody, exhibits a cytoplasmic staining pattern with perinuclear Golgi accentuation and very rarely membranous. Typically, this antibody is utilized for identifying T cell and NK cell lymphomas in FFPE tissues (please refer to representative staining photos). While the Cd3 surface antibody is commonly used in flow cytometry for membranous CD3 detection, the CD3 epsilon cytoplasmic is generally used in FFPE tissue, as is often done for IHC.
103R-9
CD3 (MRQ-39) Rabbit Monoclonal Antibody
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
100
500
conjugado
unconjugated
forma do anticorpo
culture supernatant
tipo de produto de anticorpo
primary antibodies
clone
MRQ-39, monoclonal
descrição
For In Vitro Diagnostic Use in Select Regions (See Chart)
Formulário
buffered aqueous solution
reatividade de espécies
human
embalagem
pkg of 0.1 mL concentrate (103r-94)
pkg of 0.5 mL concentrate (103R-95)
pkg of 1.0 mL concentrate (103R-96)
pkg of 1.0 mL predilute (103R-97)
pkg of 7.0 mL predilute (103R-98)
fabricante/nome comercial
Cell Marque®
IVD
for in vitro diagnostic use
técnica(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)
Isotipo
IgG1
controle
tonsil
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
visualização
membranous
Informações sobre genes
human ... CD3E(916)
Categorias relacionadas
Descrição geral
Anti-CD3 has been considered the best all around T-cell marker. This antibody reacts with an antigen present in early thymocytes. The positive staining of this marker may represent a sign of early commitment to the T-Cell lineage.
Qualidade
 IVD |  IVD |  IVD |  RUO |
Ligação
CD3 Positive Control Slides, Product No. 103S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
forma física
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Nota de preparo
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Outras notas
For Technical Service please contact: 800-665-7284 or email: [email protected]
Informações legais
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
Não está encontrando o produto certo?
Experimente o nosso Ferramenta de seleção de produtos.
Escolha uma das versões mais recentes:
Certificados de análise (COA)
Lot/Batch Number
Não está vendo a versão correta?
Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
SM Denning, et al.
Leucocyte Typing III, 144-147 (1987)
Kennosuke Karube et al.
The American journal of surgical pathology, 27(10), 1366-1374 (2003-09-26)
We studied the morphologic, immunohistochemical, and clinical characteristics of 158 cases of lymphoblastic lymphoma. Based on immunophenotyping and cell lineage, cases were classified into B-cell type (CD20,CD19 or CD79a+, n = 53), T-cell type (surface CD3+, n = 84), and
Ahmet Dogan et al.
The American journal of surgical pathology, 27(7), 903-911 (2003-06-27)
Occasionally, primary large B-cell lymphomas (LBLs) arising in the spleen present with a micronodular pattern involving the splenic white pulp but sparing the red pulp. Histologically, the nodules contain scattered large B cells in a background of numerous T cells
Ulla Axdorph et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 110(5), 379-390 (2002-06-22)
Morphologically, T-cell-rich B-cell lymphoma (TCRB-NHL) may be indistinguishable from Hodgkin's disease (HD). Immunophenotyping may be helpful in the separation of these entities. TCRB-NHL is occasionally misdiagnosed and treated as HD. However, information is limited regarding clinical characteristics and outcome of
E A Clark et al.
Immunology today, 10(7), 225-228 (1989-07-01)
During 1987, striking advances were made in defining the receptors and ligands for cell-to-cell adhesion interactions involving leukocytes. In 1988, two major leukocyte differentiation antigens, CD10 (cALLA) and CD45 (LCA, T200), were shown to be enzymes while two other markers
-
Could you confirm if the CD3 clone (Catalog #103R-96) recognizes epsilon?
1 answer-
Helpful?
-
Active Filters
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica
