04632

N-Methyl-L-tyrosine

≥98% (HPLC)

• Sinônimo(s): (S)-3-(4-Hydroxyphenyl)-2-(methylamino)propionic acid, N-Me-Tyr-OH, Surinamine
• Fórmula empírica (Notação de Hill): C₁₀H₁₃NO₃
• Número CAS: 537-49-5
• Peso molecular: 195.22
• Beilstein: 2646795
• Número CE: 208-670-8
• Número MDL: MFCD00238322
• Código UNSPSC: 12352202
• ID de substância PubChem: 329747962

Propriedades

• Ensaio: ≥98% (HPLC)
• forma: powder or crystals
• atividade óptica: [α]/D +16.0±1.0°, c = 1 in 1 M HCl
• composição: carbon, 60.7-62.3% ; nitrogen, 6.9-7.5%
• cor: colorless to white
• aplicação(ões): cell analysis
• cadeia de caracteres SMILES: CN[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C10H13NO3/c1-11-9(10(13)14)6-7-2-4-8(12)5-3-7/h2-5,9,11-12H,6H2,1H3,(H,13,14)/t9-/m0/s1
• chave InChI: AXDLCFOOGCNDST-VIFPVBQESA-N

Descrição

Aplicação

N-Methyl-L-tyrosine was used in experiments as a control group to show that methylation of the imino group in N-p-phenylpropionyl-L-tyrosine eliminates its inhibitory effect on the firing of the giant neurone of the giant African snail.

Ações bioquímicas/fisiológicas

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319
• Declarações de precaução: P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable