If using a validated method, there will not be any false positives for methamphetamine or amphetamines. False positives can occur if doing a R&D assay and using non-validated methods.
PHR1173
N-Acetyl-L-tyrosine
Pharmaceutical Secondary Standard; Certified Reference Material
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1 G
R$ 548,00
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1 G
R$ 548,00
About This Item
Fórmula linear:
4-(HO)C6H4CH2CH(NHCOCH3)CO2H
Número CAS:
Peso molecular:
223.23
Beilstein:
2697172
Número CE:
Número MDL:
Código UNSPSC:
41116107
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.24
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grau
certified reference material
pharmaceutical secondary standard
Nível de qualidade
Agency
traceable to USP 1010106
família API
acetyltyrosine
Certificado de análise (CofA)
current certificate can be downloaded
técnica(s)
HPLC: suitable
gas chromatography (GC): suitable
pf
149-152 °C (lit.)
aplicação(ões)
pharmaceutical (small molecule)
Formato
neat
temperatura de armazenamento
2-8°C
cadeia de caracteres SMILES
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI
1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
chave InChI
CAHKINHBCWCHCF-JTQLQIEISA-N
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Descrição geral
N-Acetyl-L-tyrosine is an acetyl derivative of the amino acid, L-tyrosine. It is freely soluble in water compared to L-tyrosine and is commonly used as a parenteral nutrition supplement.[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Aplicação
N-Acetyl-L-tyrosine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by titrimetry[2] and high performance liquid chromatography.[3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Nota de análise
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Outras notas
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
Nota de rodapé
To see an example of a Certificate of Analysis for this material enter LRAA6108 in the slot below. This is an example certificate only and may not be the lot that you receive.
produto relacionado
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Escolha uma das versões mais recentes:
Certificados de análise (COA)
Lot/Batch Number
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N-Acetyltyrosine
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 1641-1642 (2017)
N-Acetyltyrosine
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 38(3)(5), 4702-4702 (2018)
Investigation of DNA-protein cross-link formation between lysozyme and oxanine by mass spectrometry.
Hauh-Jyun Candy Chen et al.
Chembiochem : a European journal of chemical biology, 9(7), 1074-1081 (2008-03-21)
Reactive nitrogen species are implicated in inflammatory diseases and cancers. Oxanine (Oxa) is a DNA lesion product originating from the guanine base through exposure to nitric oxide, nitrous acid, or N-nitrosoindoles. Oxanine was found to mediate formation of DNA-protein cross-links
Sandrine Perrier et al.
Journal of the American Chemical Society, 131(34), 12458-12465 (2009-08-08)
Steady-state (1)H photo-chemically induced dynamic nuclear polarization (CIDNP) experiments were conducted at 14.1 T on deoxygenated (buffered pH 7) aqueous solutions of [Ru(phen)(3)](2+), [Ru(tap)(2)(phen)](2+), and [Ru(tap)(3)](2+) (tap = 1,4,5,8-tetraazaphenanthrene; phen = 1,10-phenanthroline) in the presence of guanosine-5'-monophosphate or N-acetyltyrosine. For
V Kahn et al.
Pigment cell research, 11(1), 24-33 (1998-04-02)
N-acetyl tyrosine (NAT) is hydroxylated by mushroom tyrosinase and the N-acetyl dopa formed is oxidized by the enzyme to N-acetyl dopaquinone (lambda max = 390 +/- 10 nm). H2O2 and NH2OH each shortened the lag period of NAT hydroxylation by
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