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Y0000112

Lobeline hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

(−)-Lobeline hydrochloride, α-Lobeline hydrochloride, L-Lobeline hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C22H27NO2 · HCl
Número CAS:
134-63-4
Peso molecular:
373.92
Beilstein:
3920196
Número MDL:
MFCD00082455
Código UNSPSC:
41116107
ID de substância PubChem:
329830851
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

lobeline

fabricante/nome comercial

EDQM

pf

183-185 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl[H].CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3

InChI

1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1

chave InChI

MKMYPTLXLWOUSO-NFQNBQCWSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Lobeline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301 + H331

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Yu-Chieh David Chen et al.
Cell reports, 29(4), 961-973 (2019-10-24)
Taste drives appropriate food preference and intake. In Drosophila, taste neurons are housed in both external and internal organs, but the latter have been relatively underexplored. Here, we report that Poxn mutants with a minimal taste system of pharyngeal neurons
Monzurul Amin Roni et al.
Psychopharmacology, 231(15), 2989-2998 (2014-04-01)
Evidence suggests that neuronal nicotinic acetylcholine receptor (nAChR) ligand lobeline has antidepressant-like properties. The present study investigated the effects of lobeline on nicotine withdrawal-induced depression-like behavior. Adult C57BL/6J mice were exposed to nicotine (200 μg/ml) in drinking solution for 3 weeks. During
Yan Chen et al.
Current biology : CB, 24(17), 1969-1977 (2014-08-19)
Natural foods contain not only nutrients, but also nonnutritious and potentially harmful chemicals. Thus, animals need to evaluate food content in order to make adequate feeding decisions. Here, we investigate the effects of acids on the taste neuron responses and

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