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Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride

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About This Item

Fórmula linear:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
Número CAS:
543-15-7
Peso molecular:
181.70
Beilstein:
3673011
Número MDL:
MFCD00013015
Código UNSPSC:
41116107
ID de substância PubChem:
329830831
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

pharmaceutical primary standard

família API

heptaminol

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl.CC(N)CCCC(C)(C)O

InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

chave InChI

JZNBMCOSOXIZJB-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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B Pourrias
Annales pharmaceutiques francaises, 49(3), 127-138 (1991-01-01)
Heptaminol hydrochloride is widely used for the treatment for orthostatic hypotension. It continues to elicit controversy as to its mode of action since Loubatières (1951) described its powerful inotropic action on an ischaemic preparation. Twenty five years later it has
[A comparison of various phlebotonic agents on human endothelial cells of veins subjected to hypoxia].
J Remacle et al.
Phlebologie, 44(4), 881-889 (1991-11-01)
D Milon et al.
Fundamental & clinical pharmacology, 4(6), 695-705 (1990-01-01)
Heptaminol is a molecule with experimental cardiovascular analeptic properties. In this double-blind vs placebo trial, the potency, so far unproven, of the injectable form of a 626 mg dose of heptaminol chlorhydrate on spontaneous or induced orthostatic hypotension (OH), was
P D Drumheller et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(5), 1258-1265 (1991-09-01)
An endothelial cell monolayer with a single mechanically lysed cell was used as a model to examine the extent, kinetics, and nature of local calcium mobilization in the neighborhood of a wound. Individual endothelial cells from confluent monolayers were mechanically
N Peineau et al.
British journal of pharmacology, 107(1), 104-108 (1992-09-01)
1. The effects of heptaminol on calcium current amplitude and characteristics were studied in single ventricular myocytes of guinea-pig by use of the whole cell configuration of the patch clamp technique. 2. A concentration-dependent decrease in ICa amplitude was observed.
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