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Documentos Principais

T9159

Sigma-Aldrich

Ácido tricloroacético

BioXtra, ≥99.0%

Sinônimo(s):

TCA

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R$ 522,00
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R$ 844,00
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100 G
R$ 522,00
250 G
R$ 844,00
500 G
R$ 1.335,00

About This Item

Fórmula linear:
Cl3CCOOH
Número CAS:
Peso molecular:
163.39
Beilstein:
970119
Número CE:
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NB.22

R$ 522,00


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grau

BioPerformance Certified

Nível de qualidade

densidade de vapor

<1 (vs air)

pressão de vapor

1 mmHg ( 51 °C)

linha de produto

BioXtra

Ensaio

≥99.0%

Impurezas

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

resíduo de ignição

≤0.03%

índice de refração

n20/D 1.62 (lit.)

p.e.

196 °C (lit.)

pf

54-58 °C (lit.)

solubilidade

H2O: 0.5 M at 20 °C, clear, colorless

densidade

1.62 g/mL at 25 °C (lit.)

traços de ânion

sulfate (SO42-): ≤0.05%

traços de cátion

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.01%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

chave InChI

YNJBWRMUSHSURL-UHFFFAOYSA-N

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Descrição geral

Trichloroacetic acid (TCA) is an important metabolic product of trichloroethylene (TCE) metabolism.

Aplicação

Usado tradicionalmente para precipitar proteínas. Foi usado para determinar a concentração proteica por precipitação quantitativa. Usado como descalcificador e fixador em microscopia.
Trichloroacetic acid has been used:
  • for protein precipitation[1]
  • as a component in the extract solution used for the measurement of malondialdehyde and glutathione[2]
  • to precipitate the transfected and treated cells in [3H]-thymidine incorporation assay[3]

Ações bioquímicas/fisiológicas

TCA might act as a carcinogen, targeting liver.[4] It might be used as an acid decalcifying agent. TCA helps in nuclear staining.[5]

Pictogramas

CorrosionEnvironment

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Código de classe de armazenamento

8B - Non-combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

>235.4 °F - closed cup

Ponto de fulgor (°C)

> 113 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Circulating fibrocytes stabilize blood vessels during angiogenesis in a paracrine manner
Li J, et al.
The American Journal of Pathology, 184(2), 556-571 (2014)
Analysis of malondialdehyde, chlorophyll proline, soluble sugar, and glutathione content in Arabidopsis seedling
Zhang Z and Huang R
Bio-protocol, 3, e817-e817 (2013)
Rapid analysis of total plasma homocysteine by tandem mass spectrometry
Tuschl K, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 351(1-2), 139-141 (2005)
Histophatologic Techniques (2006)
Bo Chen et al.
Translational stroke research, 10(1), 91-103 (2018-03-24)
The transient receptor potential melastatin 4 (TRPM4) channel has been suggested to play a key role in the treatment of ischemic stroke. However, in vivo evaluation of TRPM4 channel, in particular by direct channel suppression, is lacking. In this study

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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