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S2159100

Sulfapyridine

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

4-Amino-N-[2-pyridyl]benzene sulfonamide, N1-(Pyridin-2-yl)sulfanilamide

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About This Item

Fórmula empírica (Notação de Hill):
C11H11N3O2S
Número CAS:
144-83-2
Peso molecular:
249.29
Beilstein:
222065
Número MDL:
MFCD00038036
Código UNSPSC:
41116107
ID de substância PubChem:
329824511
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

sulfapyridine

fabricante/nome comercial

EDQM

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2

InChI

1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

chave InChI

GECHUMIMRBOMGK-UHFFFAOYSA-N

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Descrição geral

Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Sulfapyridine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Health hazard
GHS08

Palavra indicadora

Warning

Frases de perigo

H361fd

Classificações de perigo

Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

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Certificados de análise (COA)

Lot/Batch Number

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Dapsone and sulfapyridine.
J Uetrecht
Clinics in dermatology, 7(3), 111-120 (1989-07-01)
Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicylic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis.
Volin, Michael V., et al.
Arthritis and Rheumatism, 42.9, 1927-1935 (1999)
U Paniker et al.
Dermatologic clinics, 19(1), 79-86 (2001-01-13)
Dapsone and sulfapyridine are structurally related compounds with anti-microbial and anti-inflammatory effects. Dapsone remains the most important drug for leprosy and is useful in the prophylaxis of Pneumocystis pneumonia in patients with HIV disease. The medical treatment of choice for
Shaojun Yang et al.
The Journal of pharmacology and experimental therapeutics, 352(3), 529-540 (2015-01-01)
Sepiapterin reductase (SPR) catalyzes the reduction of sepiapterin to dihydrobiopterin (BH2), the precursor for tetrahydrobiopterin (BH4), a cofactor critical for nitric oxide biosynthesis and alkylglycerol and aromatic amino acid metabolism. SPR also mediates chemical redox cycling, catalyzing one-electron reduction of
M Díaz-Álvarez et al.
Journal of chromatography. A, 1357, 158-164 (2014-05-02)
In this work, molecularly imprinted polymer (MIP) beads have been prepared and evaluated for the development of a supported liquid membrane-protected micro-solid phase extraction method for the analysis of sulfonamides (SAs) in aqueous samples. The performance of MIP beads was
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