PHR1366

Dibutyl Phthalate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Dibutyl phthalate, n-Butyl phthalate, DBP, Phthalic acid dibutyl ester
• Fórmula linear: C₆H₄-1,2-[CO₂(CH₂)₃CH₃]₂
• Número CAS: 84-74-2
• Peso molecular: 278.34
• Beilstein: 1914064
• Número CE: 201-557-4
• Número MDL: MFCD00009441
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823345
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to Ph. Eur. D1010000; traceable to USP 1187080
• densidade de vapor: 9.6 (vs air)
• pressão de vapor: 1 mmHg ( 147 °C)
• família API: dibutyl phthalate
• Certificado de análise (CofA): current certificate can be downloaded
• temperatura de autoignição: 756 °F
• Lim. expl.: 0.47 %, 236 °F
• embalagem: pkg of 1 g
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.492 (lit.)
• pb: 340 °C (lit.)
• pf: −35 °C (lit.)
• densidade: 1.043 g/mL at 25 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: CCCCOC(=O)c1ccccc1C(=O)OCCCC
• InChI: 1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
• chave InChI: DOIRQSBPFJWKBE-UHFFFAOYSA-N

Descrição

Descrição geral

Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol. It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Plasticizer

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H360FD,H410
• Declarações de precaução: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 339.8 °F
• Ponto de fulgor (°C): 171 °C