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P3800000

Proxyphylline

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

7-(β-Hydroxypropyl)theophylline, (1,3-Dimethyl-7-[2-hydroxypropyl]-2,6-dioxopurine), Proxyphylline

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About This Item

Fórmula empírica (Notação de Hill):
C10H14N4O3
Número CAS:
603-00-9
Peso molecular:
238.24
Número MDL:
MFCD00022833
Código UNSPSC:
41116107
ID de substância PubChem:
329820192
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

proxyphylline

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(O)Cn1cnc2N(C)C(=O)N(C)C(=O)c12

InChI

1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3

chave InChI

KYHQZNGJUGFTGR-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Proxyphylline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P301 + P312 + P330

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Lot/Batch Number

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H Magnussen et al.
Deutsche medizinische Wochenschrift (1946), 111(1), 15-19 (1986-01-03)
In study I, carried out on 9 asthmatics to investigate whether the bronchodilator and protective effect of intravenous theophylline, dissolved in ethylene diamine (T.E.) or proxyphylline and diprophylline (T.P.D.), showed different dose-effect relationships, 100 mg theophylline with T.E., T.P.D. or
Linfeng Wu et al.
International journal of pharmaceutics, 349(1-2), 1-10 (2007-09-11)
Delayed release systems find applications in chronotherapeutics and colon-specific delivery. They have also been considered suitable carriers for the oral delivery of peptides and proteins. In prior work, our research group has reported surface crosslinking as an effective technique to
H Magnussen et al.
Chest, 90(5), 722-725 (1986-11-01)
To compare the acute bronchodilator effect of increasing doses of intravenous theophylline and inhaled beta adrenergic agonists, we administered intravenous theophylline dissolved in ethylenediamine or proxyphylline and diprophylline or placebo in a double blind fashion to nine asthmatics on three
R Duclos et al.
International journal of pharmaceutics, 182(2), 145-154 (1999-05-26)
Three polyol behenates with similar melting points (MP) and different hydrophilic-lipophilic balances (HLB) were studied (MP/HLB: 70/02, 63/05 and 57/13). After melting at MP+30 degrees C, the rheological behaviour of behenates was determined by adjustment of the rheograms to the
V Ratsimbazafy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 48(3), 247-252 (1999-12-28)
Mixtures of Gelucires 50/02 and 50/13 showing different hydrophilic-lipophilic balances (HLB) and of proxyphylline were used to prepare suspensions at a concentration of 25% and to manufacture extended release hard gelatin capsules by cooling. The rheological behaviors of Gelucire mixtures
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