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H0800000

Homatropine hydrobromide

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

DL-Homatropine hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide, Tropine mandelate hydrobromide

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About This Item

Fórmula empírica (Notação de Hill):
C16H21NO3 · HBr
Número CAS:
51-56-9
Peso molecular:
356.25
Número MDL:
MFCD00012676
Código UNSPSC:
41116107
ID de substância PubChem:
329815135
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

pharmaceutical primary standard

família API

homatropine

fabricante/nome comercial

EDQM

pf

214-217 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

chave InChI

DWSGTFTVBLXELC-UHFFFAOYSA-N

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Descrição geral

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.[1]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Emergency medicine Australasia : EMA, 23(2), 231-231 (2011-04-15)
Colin C K Chan et al.
Clinical & experimental ophthalmology, 33(3), 296-297 (2005-06-04)
A case is reported of formation of a dense intraocular membrane following combined phacoemulsification-trabeculectomy surgery. The membrane might have originated from a loose piece of pigment epithelium or might have resulted from dense pigment deposition on a postoperative pupillary membrane.
Sean M Bryant et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2(4), 156-159 (2007-12-12)
Most hospitals lack a sufficient supply of atropine to treat, simultaneously, patients poisoned with multiple organophosphorous compound (OC) or nerve agent. The presence of a ubiquitous alternate antidote would prove useful if mass poisoning occurred. Our objective was to evaluate
N George et al.
Autonomic & autacoid pharmacology, 30(3), 173-177 (2010-01-21)
This study investigated whether four anticholinergics which are not clinically used for relaxing the urinary bladder detrusor muscle inhibit the contraction of isolated caprine (goat) detrusor muscle: cyclopentolate (100 nm), homatropine (5 microm), ipratropium (500 nm) and valethamate (1 microm).
Brian M Thome et al.
Electrophoresis, 28(10), 1477-1487 (2007-05-12)
True moving bed electrophoresis has been shown to be an effective technique for the bench-scale separation of enantiomers, and it is desired to increase the maximum possible throughput attainable with the process by using electric field gradients. Homatropine enantiomer separations
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