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F0290000

Flutrimazole

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole

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About This Item

Fórmula empírica (Notação de Hill):
C22H16F2N2
Número CAS:
119006-77-8
Peso molecular:
346.37
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

flutrimazole

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

InChI

1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H

chave InChI

QHMWCHQXCUNUAK-UHFFFAOYSA-N

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Flutrimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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del Palacio et al.
Mycoses, 38(9-10), 395-403 (1995-09-01)
In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% solution were compared with bifonazole 1% solution, applied once daily for 4 weeks, in 40 patients with culturally proven dermatophytosis or cutaneous candidosis. Forty patients with mycologically proven
J García Rafanell et al.
Arzneimittel-Forschung, 42(6), 836-840 (1992-06-01)
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (MIC = 0.025-5.0 micrograms/ml). In most of these
A Alomar et al.
Dermatology (Basel, Switzerland), 190(4), 295-300 (1995-01-01)
Flutrimazole is a new imidazole derivate. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. To compare the efficacy and tolerability of flutrimazole cream 1%
Synthesis and antifungal activity of a series of difluorotritylimidazoles.
J Bartrolí et al.
Arzneimittel-Forschung, 42(6), 832-835 (1992-06-01)
[Facial dermatophytide reaction].
B Monteagudo Sánchez et al.
Anales de pediatria (Barcelona, Spain : 2003), 68(4), 411-412 (2008-04-09)
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