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Documentos Principais

E4009

Sigma-Aldrich

Eosin Y

Dye content ~99%, Powder

Sinônimo(s):

2′,4′,5′,7′-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43

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5 G
R$ 736,00
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R$ 3.190,00

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Previsão de entrega em20 de junho de 2025


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5 G
R$ 736,00
25 G
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About This Item

Fórmula empírica (Notação de Hill):
C20H8Br4O5
Número CAS:
Peso molecular:
647.89
Número do índice de cores:
45380:2
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.47

R$ 736,00


Previsão de entrega em20 de junho de 2025


Solicite uma grande encomenda

Nome do produto

Eosin Y, Dye content ~99 %

Formulário

powder

Nível de qualidade

composição

Dye content, ~99%

cor

light red to red/pink

solubilidade

ethanol: 1 mg/mL

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br

InChI

1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

chave InChI

DBZJJPROPLPMSN-UHFFFAOYSA-N

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Aplicação

Eosin Y has been used as a stain:
  • to determine the location of the brain sections[1]
  • for staining of fixed liver tissue[2]
  • for histological examination of brain sections from the dorsal hippocampus[3]

Ações bioquímicas/fisiológicas

Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.[4][5]

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Certificados de análise (COA)

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Visite a Biblioteca de Documentos

Antonello Mai et al.
Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)
A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine
An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.
Young LW, et al.
Histochemistry and Cell Biology, 144, 321-321 (2015)
Florian Ménard et al.
Bioorganic & medicinal chemistry, 17(22), 7647-7657 (2009-10-13)
This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
Gao Z, et al.
The Journal of Biological Chemistry, 284, 18368-18368 (2009)
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Sun J, et al.
International Journal of Molecular Medicine, 30, 739-739 (2012)

Questions

1–2 of 2 Questions  
  1. What is the purity level for product E4009 and can it be added to CoA?

    1 answer
    1. t is not possible to add a purity specification to Eosin Y free acid because no purity tests are performed

      Helpful?

  2. Is there a sample protocol for this product ? There id low solubility of E4009 in even ethanol (1 mg/mL) in that case how to make the usual eosin concentration of 1-5% w/v for use in an H&E staining reaction.

    1 answer
    1. It is not feasible to dissolve catalog number E4009 to a concentration of 1 to 5% in alcohol. For H&E staining or staining sperm for viability, Eosin Y disodium salt is typically used, rather than Eosin Y free acid. Dry dyes, available under catalog numbers E4382 or 861006, are also used, along with various solutions for H&E staining, which also utilize only Eosin Y disodium salt. A 5% Eosin Y solution is available with the catalog number 318906, which is also formulated with Eosin Y disodium salt.

      Helpful?

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